Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Mar 5:15:1297164.
doi: 10.3389/fendo.2024.1297164. eCollection 2024.

Worldwide productivity and research trend of publications concerning SIAD: a bibliometric study

Xiaodan Wei #  1 , Weiyuan Pan #  2 , Shaocong Lun  2 , Yuexuan Wu  2 , Yushi Chen  2 , Taoshan Feng  2 , Meilian Liu  3 , Xiaoming Chen #  4   5
Affiliations

Worldwide productivity and research trend of publications concerning SIAD: a bibliometric study

Xiaodan Wei et al. Front Endocrinol (Lausanne). .

Abstract

Background: Syndrome of inappropriate antidiuretic(SIAD) occurs secondary to various diseases, which is characterised by hypotonic hyponatremia and impaired urinary diluting capacity. Research on SIAD in both domestic and international contexts has a long history. This study objectively and comprehensively analyses the research trends, hotspots and development of SIAD research of the past 20 years using the method of bibliometric analysis.

Methods: The 2003-2022 data in the Web of Science Core Collection database were searched. The Bibliometrix software package, VOSviewer and CiteSpace were used to mine, extract and visualise the retrieved literature, and the generated maps were used in analysing the main topics and trends in the field of SIAD research.

Results: A total of 1215 articles published in 623 journals were included in the analysis, with a total of 18,886 citations. Results showed that the research output on SIAD has continuously increased in the past 20 years, and the United States had the highest number of publications and citations. Keywords with the highest burst strength in recent years were the most mentioned keywords, in addition to the search terms 'hyponatremia', 'covid-19', and 'mortality'. Thus, the relationship among SIAD, covid-19 and mortality may become research frontiers and trends. Fifteen milestone articles were identified through co-citation analysis, which mainly focused on the pathophysiology and treatment of SIAD.

Conclusion: Based on bibliometric analysis and knowledge mapping, this study summarises development trends in the field of SIAD research, providing references for current and future research into SIAD.

Keywords: CiteSpace; SIAD; VOSviewer; bibliometric analysis; development.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Production of annual articles. (A) The annual scientific production in SIAD research from 2003 to 2022. The blue column represents the annual articles and the orange curve represents the cumulative articles. (B) The comparison of publication growth rate between SIAD with diabetic foot ulcers and diabetes remission. The red curve represents the annual articles in SIAD research. The light blue curve represents the annual articles in diabetic foot ulcers research from 2004 to 2020 and the light green curve represents the annual articles in diabetes remission research from 2000 to 2022.
Figure 2
Figure 2
Analysis of countries engaged in SIAD. (A) Geographical distribution of article publications related to SIAD. The depth of colour matched with the number of articles. (B) Cooperation of countries or regions on SIAD research from 2003 to 2022.Each node represents a country or region. The link size refers to the cooperation intensity. The size of the node is proportional to the total link strength.
Figure 3
Figure 3
Analysis of authors and institutions engaged in SIAD. (A) The visualization map of collaborations between institutions. The lines between nodes represent cooperation between institutions. Each node represents one institution. The size of the node is proportional to the number of documents. (B) The visualization map of collaborations between institutions. The size of the node is proportional to the number of citations.
Figure 4
Figure 4
The dual map of journals published on SIAD. Citing journals are on the right, cited journal is on the left, and lines represent the citation relationship.
Figure 5
Figure 5
The density visualization map of the top 73 co-cited references from 2003 to 2022. Red references represent the highest frequency.
Figure 6
Figure 6
Timeline of part of landmark achievements in SIAD research.
Figure 7
Figure 7
The bibliometric analysis of the keywords. (A) The top 10 most common keywords. (B) Co-occurrence analysis of keywords shown in different clusters in SIAD area. Different clusters are represented by different colours. Each node represents one keyword. The size of the node is proportional to the frequency of keyword. The line between two nodes represents that both keywords occurred in one article. (C) The visualization map of time when a keyword appeared. Keywords in blue appeared earlier than that in red. (D) The density visualization map of Keyword distribution according to the average frequency of occurrence. Red keywords represent the highest frequency.
Figure 8
Figure 8
The top 10 Keywords with the strongest citation bursts in SIAD studies.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Warren AM, Grossmann M, Christ-Crain M, Russell N. Syndrome of inappropriate antidiuresis: from pathophysiology to management. Endocr Rev. (2023) 44:819–61. doi: 10.1210/endrev/bnad010 - DOI - PMC - PubMed
    1. Adrogué HJ, Madias NE. The syndrome of inappropriate antidiuresis. N Engl J Med. (2023) 389:1499–509. doi: 10.1056/NEJMcp2210411 - DOI - PubMed
    1. Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, et al. . Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol. (2014) 170:G1–47. doi: 10.1530/EJE-13-1020 - DOI - PubMed
    1. Renneboog B, Musch W, Vandemergel X, Manto MU, Decaux G. Mild chronic hyponatremia is associated with falls, unsteadiness, and attention deficits. Am J Med. (2006) 119:71.e71–78. doi: 10.1016/j.amjmed.2005.09.026 - DOI - PubMed
    1. Hoorn EJ, Rivadeneira F, van Meurs JB, Ziere G, Stricker BH, Hofman A, et al. . Mild hyponatremia as a risk factor for fractures: the Rotterdam Study. J Bone Miner Res. (2011) 26:1822–8. doi: 10.1002/jbmr.380 - DOI - PubMed