Ischaemic and viability testing for guiding PCI are overrated: pros and cons

doi:10.4244/EIJ-E-24-00005

. 2024 Mar 18;20(6):e341-e343.

doi: 10.4244/EIJ-E-24-00005.

Ischaemic and viability testing for guiding PCI are overrated: pros and cons

Margaret B McEntegart¹, Anja Oksnes², Xavier Carrillo³, Victoria Delgado^{3

4}

Affiliations

¹ Columbia University Irving Medical Center, New York, NY, USA.
² Haukeland University Hospital, Bergen, Norway.
³ Heart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.
⁴ Centre of Comparative Medicine and Bioimaging, Badalona, Spain.

PMID: 38506743
PMCID: PMC10941666
DOI: 10.4244/EIJ-E-24-00005

Ischaemic and viability testing for guiding PCI are overrated: pros and cons

Margaret B McEntegart et al. EuroIntervention. 2024.

. 2024 Mar 18;20(6):e341-e343.

doi: 10.4244/EIJ-E-24-00005.

Authors

Margaret B McEntegart¹, Anja Oksnes², Xavier Carrillo³, Victoria Delgado^{3

4}

Affiliations

¹ Columbia University Irving Medical Center, New York, NY, USA.
² Haukeland University Hospital, Bergen, Norway.
³ Heart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.
⁴ Centre of Comparative Medicine and Bioimaging, Badalona, Spain.

PMID: 38506743
PMCID: PMC10941666
DOI: 10.4244/EIJ-E-24-00005

No abstract available

PubMed Disclaimer

Conflict of interest statement

M. McEntegart is a consultant for Boston Scientific, Shockwave Medical, and Teleflex. A. Oknes is a consultant for Boston Scientific.

V. Delgado received speaker fees from Edwards Lifesciences, GE HealthCare, Medtronic, Philips, and Novartis; and consulting fees from Edwards Lifesciences, MSD, and Novo Nordisk. X. Carrillo has no conflicts of interest to declare.

References

1. Reynolds HR, Shaw LJ, Min JK, Page CB, Berman DS, Chaitman BR, Picard MH, Kwong RY, O’Brien SM, Huang Z, Mark DB, Nath RK, Dwivedi SK, Smanio PEP, Stone PH, Held C, Keltai M, Bangalore S, Newman JD, Spertus JA, Stone GW, Maron DJ, Hochman JS. Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity. Circulation. 2021;144:1024–38. - PMC - PubMed
1. O’Fee K, Panza JA, Brown DL. Association of Inducible Myocardial Ischemia With Long-Term Mortality and Benefit From Coronary Artery Bypass Graft Surgery in Ischemic Cardiomyopathy: Ten-Year Follow-Up of the STICH Trial. Circulation. 2021;143:205–7. - PubMed
1. Shaw LJ, Weintraub WS, Maron DJ, Hartigan PM, Hachamovitch R, Min JK, Dada M, Mancini GB, Hayes SW, O’Rourke RA, Spertus JA, Kostuk W, Gosselin G, Chaitman BR, Knudtson M, Friedman J, Slomka P, Germano G, Bates ER, Teo KK, Boden WE, Berman DS. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention. Am Heart J. 2012;164:243–50. - PubMed
1. Panza JA, Ellis AM, Al-Khalidi HR, Holly TA, Berman DS, Oh JK, Pohost GM, Sopko G, Chrzanowski L, Mark DB, Kukulski T, Favaloro LE, Maurer G, Farsky PS, Tan RS, Asch FM, Velazquez EJ, Rouleau JL, Lee KL, Bonow RO. Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy. N Engl J Med. 2019;381:739–48. - PMC - PubMed
1. Perera D, Ryan M, Morgan HP, Greenwood JP, Petrie MC, Dodd M, Weerackody R, O’Kane PD, Masci PG, Nazir MS, Papachristidis A, Chahal N, Khattar R, Ezad SM, Kapetanakis S, Dixon LJ, De Silva, McDiarmid AK, Marber MS, McDonagh T, McCann GP, Clayton TC, Senior R, Chiribiri A REVIVED-BCIS2 Investigators. Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: A Prespecified Secondary Analysis of the REVIVED-BCIS2 Trial. JAMA Cardiol. 2023;8:1154–61. - PMC - PubMed

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[1] Reynolds HR, Shaw LJ, Min JK, Page CB, Berman DS, Chaitman BR, Picard MH, Kwong RY, O’Brien SM, Huang Z, Mark DB, Nath RK, Dwivedi SK, Smanio PEP, Stone PH, Held C, Keltai M, Bangalore S, Newman JD, Spertus JA, Stone GW, Maron DJ, Hochman JS. Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity. Circulation. 2021;144:1024–38. - PMC - PubMed

[2] Reynolds HR, Shaw LJ, Min JK, Page CB, Berman DS, Chaitman BR, Picard MH, Kwong RY, O’Brien SM, Huang Z, Mark DB, Nath RK, Dwivedi SK, Smanio PEP, Stone PH, Held C, Keltai M, Bangalore S, Newman JD, Spertus JA, Stone GW, Maron DJ, Hochman JS. Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity. Circulation. 2021;144:1024–38. - PMC - PubMed

[3] O’Fee K, Panza JA, Brown DL. Association of Inducible Myocardial Ischemia With Long-Term Mortality and Benefit From Coronary Artery Bypass Graft Surgery in Ischemic Cardiomyopathy: Ten-Year Follow-Up of the STICH Trial. Circulation. 2021;143:205–7. - PubMed

[4] O’Fee K, Panza JA, Brown DL. Association of Inducible Myocardial Ischemia With Long-Term Mortality and Benefit From Coronary Artery Bypass Graft Surgery in Ischemic Cardiomyopathy: Ten-Year Follow-Up of the STICH Trial. Circulation. 2021;143:205–7. - PubMed

[5] Shaw LJ, Weintraub WS, Maron DJ, Hartigan PM, Hachamovitch R, Min JK, Dada M, Mancini GB, Hayes SW, O’Rourke RA, Spertus JA, Kostuk W, Gosselin G, Chaitman BR, Knudtson M, Friedman J, Slomka P, Germano G, Bates ER, Teo KK, Boden WE, Berman DS. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention. Am Heart J. 2012;164:243–50. - PubMed

[6] Shaw LJ, Weintraub WS, Maron DJ, Hartigan PM, Hachamovitch R, Min JK, Dada M, Mancini GB, Hayes SW, O’Rourke RA, Spertus JA, Kostuk W, Gosselin G, Chaitman BR, Knudtson M, Friedman J, Slomka P, Germano G, Bates ER, Teo KK, Boden WE, Berman DS. Baseline stress myocardial perfusion imaging results and outcomes in patients with stable ischemic heart disease randomized to optimal medical therapy with or without percutaneous coronary intervention. Am Heart J. 2012;164:243–50. - PubMed

[7] Panza JA, Ellis AM, Al-Khalidi HR, Holly TA, Berman DS, Oh JK, Pohost GM, Sopko G, Chrzanowski L, Mark DB, Kukulski T, Favaloro LE, Maurer G, Farsky PS, Tan RS, Asch FM, Velazquez EJ, Rouleau JL, Lee KL, Bonow RO. Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy. N Engl J Med. 2019;381:739–48. - PMC - PubMed

[8] Panza JA, Ellis AM, Al-Khalidi HR, Holly TA, Berman DS, Oh JK, Pohost GM, Sopko G, Chrzanowski L, Mark DB, Kukulski T, Favaloro LE, Maurer G, Farsky PS, Tan RS, Asch FM, Velazquez EJ, Rouleau JL, Lee KL, Bonow RO. Myocardial Viability and Long-Term Outcomes in Ischemic Cardiomyopathy. N Engl J Med. 2019;381:739–48. - PMC - PubMed

[9] Perera D, Ryan M, Morgan HP, Greenwood JP, Petrie MC, Dodd M, Weerackody R, O’Kane PD, Masci PG, Nazir MS, Papachristidis A, Chahal N, Khattar R, Ezad SM, Kapetanakis S, Dixon LJ, De Silva, McDiarmid AK, Marber MS, McDonagh T, McCann GP, Clayton TC, Senior R, Chiribiri A REVIVED-BCIS2 Investigators. Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: A Prespecified Secondary Analysis of the REVIVED-BCIS2 Trial. JAMA Cardiol. 2023;8:1154–61. - PMC - PubMed

[10] Perera D, Ryan M, Morgan HP, Greenwood JP, Petrie MC, Dodd M, Weerackody R, O’Kane PD, Masci PG, Nazir MS, Papachristidis A, Chahal N, Khattar R, Ezad SM, Kapetanakis S, Dixon LJ, De Silva, McDiarmid AK, Marber MS, McDonagh T, McCann GP, Clayton TC, Senior R, Chiribiri A REVIVED-BCIS2 Investigators. Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: A Prespecified Secondary Analysis of the REVIVED-BCIS2 Trial. JAMA Cardiol. 2023;8:1154–61. - PMC - PubMed

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Ischaemic and viability testing for guiding PCI are overrated: pros and cons

Affiliations

Ischaemic and viability testing for guiding PCI are overrated: pros and cons

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Conflict of interest statement

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