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. 2024 Mar 20;14(1):6693.
doi: 10.1038/s41598-024-57399-y.

The influence of cultivation conditions on the formation of psychoactive salvinorin A, salvinorin B, rosmarinic acid and caffeic acid in Coleus scutellarioides

Maciej Jakobina  1 , Jacek Łyczko  2 , Antoni Szumny  2 , Renata Galek  3
Affiliations

The influence of cultivation conditions on the formation of psychoactive salvinorin A, salvinorin B, rosmarinic acid and caffeic acid in Coleus scutellarioides

Maciej Jakobina et al. Sci Rep. .

Erratum in

Abstract

Coleus scutellarioides (L.) Benh. is a popular species in the world, known for its characteristic magnificent colourful leaves. The study has revealed that the contents of rosmarinic acid and caffeic acid are significantly higher in the plant tissues cultivated in vivo than when under in vitro conditions. The performed qualitative and quantitative analyses confirmed the presence (whose averaged content) of salvinorin A (6.65 µg/1 g of fresh plant) and salvinorin B (50.46 µg/1 g of fresh plant) in tissues of Coleus scutellarioides (L.) Benh. of 'Electric lime' variety. The greatest quantities of these compounds were recorded for plants cultivated in vitro on the MS medium enriched with NAA (naphthyl-1-acetic acid) at a concentration of 0.5 mg∙ dm-3. The research detected differences in the amounts of compounds between plants grown in vivo and those cultivated in vitro. Addition of plant growth regulators into the breeding medium under in vitro conditions was found affecting the amounts of compounds in plant tissues.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Coleus scutellarioides in municipal flower-beds. (Photo: M. Jakobina).
Figure 2
Figure 2
Chromatogram of salvinorin A (pink), salvinorin B (black) and caffeic acid (blue).
Figure 3
Figure 3
Chromatogram of rosmarinic acid.
Diagram 1
Diagram 1
Impact of cultivation conditions on the contents of analyzed compounds in fresh tissue: (a) salvinorin A; (b) salvinorin B; (c) caffeic acid; (d) rosmarinic acid.
Figure 4
Figure 4
In vitro cultivation of the parent plant of C. scutellarioides (L.) Benth. representing 'Electric lime' variety (Photo: M. Jakobina).
See this image and copyright information in PMC

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