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Comment
. 2024 May;23(5):337.
doi: 10.1038/d41573-024-00053-z.

AI serves up target and inhibitor for lung fibrosis

Katie Kingwell
Comment

AI serves up target and inhibitor for lung fibrosis

Katie Kingwell. Nat Rev Drug Discov. 2024 May.
No abstract available

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Comment on

  • A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models.
    Ren F, Aliper A, Chen J, Zhao H, Rao S, Kuppe C, Ozerov IV, Zhang M, Witte K, Kruse C, Aladinskiy V, Ivanenkov Y, Polykovskiy D, Fu Y, Babin E, Qiao J, Liang X, Mou Z, Wang H, Pun FW, Torres-Ayuso P, Veviorskiy A, Song D, Liu S, Zhang B, Naumov V, Ding X, Kukharenko A, Izumchenko E, Zhavoronkov A. Ren F, et al. Nat Biotechnol. 2025 Jan;43(1):63-75. doi: 10.1038/s41587-024-02143-0. Epub 2024 Mar 8. Nat Biotechnol. 2025. PMID: 38459338 Free PMC article. Clinical Trial.

References

    1. Ren, F. et al. A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nat. Biotechnol. https://doi.org/10.1038/s41587-024-02143-0 (2024)

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