SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms
- PMID: 38509328
- PMCID: PMC11093726
- DOI: 10.1038/s41592-024-02229-2
SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms
Abstract
SQANTI3 is a tool designed for the quality control, curation and annotation of long-read transcript models obtained with third-generation sequencing technologies. Leveraging its annotation framework, SQANTI3 calculates quality descriptors of transcript models, junctions and transcript ends. With this information, potential artifacts can be identified and replaced with reliable sequences. Furthermore, the integrated functional annotation feature enables subsequent functional iso-transcriptomics analyses.
© 2024. The Author(s).
Conflict of interest statement
The authors declare no competing interests
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Update of
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SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms.bioRxiv [Preprint]. 2023 Jun 3:2023.05.17.541248. doi: 10.1101/2023.05.17.541248. bioRxiv. 2023. Update in: Nat Methods. 2024 May;21(5):793-797. doi: 10.1038/s41592-024-02229-2. PMID: 37398077 Free PMC article. Updated. Preprint.
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