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Case Reports
. 2024 Feb 10:46:27-29.
doi: 10.1016/j.jdcr.2023.12.025. eCollection 2024 Apr.

Morphea-like subcutaneous panniculitis-like T-cell lymphoma

Keiko Tokuchi  1 , Teruki Yanagi  1 , Emi Inamura  1 , Takuya Kawamura  1 , Takashi Seo  1 , Yasuyuki Fujita  2 , Masao Nakagawa  3 , Ikumi Kasahara  4 , Yoshihiro Matsuno  5 , Hideyuki Ujiie  1
Affiliations
Case Reports

Morphea-like subcutaneous panniculitis-like T-cell lymphoma

Keiko Tokuchi et al. JAAD Case Rep. .
No abstract available

Keywords: cutaneous lymphoma; lupus erythematosus profundus; morphea; subcutaneous panniculitis-like T-cell lymphoma.

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Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
Clinical and histopathological findings of the first and second biopsy. A, The initial assessment reveals an indurated hyperpigmented plaque measuring 8 × 6 cm on the right chest. B and C, A skin biopsy reveals dermal and subcutaneous fat swelling with increased collagen fibers. The infiltration of dense mononuclear cells is present around the dermal appendages and subcutaneous fat without rimming. Additionally, fat necrosis is observed. (B, magnification ×40; C, magnification ×200 [upper left], and ×400 [right and lower left]). D, Multiple papules appear on the trunk and extremities (the red circle indicates the biopsy site). FDG-positron emission tomography computed tomography imaging exhibits multiple regions of FDG uptake in the subcutaneous and retroperitoneal adipose tissues throughout the body (red arrows). E, The second biopsy on one of the multiple erythematous areas with subcutaneous induration reveals dense lobular lymphoid infiltrates. Notably, adipocytes are surrounded by pleomorphic lymphocytes, which is known as “rimming” (magnification: ×40 [inset] and ×400). The squares in part labels B and E indicate that the enclosed regions are being magnified. F, The abnormal lymphocytes are positive for CD3, CD8, and T-cell intracellular antigen, but negative for CD20 (magnification ×400). TIA-1, T-cell intracellular antigen.
See this image and copyright information in PMC

References

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