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Review
. 2024 Apr;26(4):421-425.
doi: 10.1007/s11912-024-01513-w. Epub 2024 Mar 21.

Head and Neck Mucosal Melanoma: Where Are We Now?

Curtis Hanba  1   2 , Ehab Hanna  3   4
Affiliations
Review

Head and Neck Mucosal Melanoma: Where Are We Now?

Curtis Hanba et al. Curr Oncol Rep. 2024 Apr.

Abstract

Purpose of review: To highlight recent and relevant treatment considerations while managing mucosal melanoma.

Recent findings: Evidence is building to support the use of targeted therapy and immunotherapy while managing mucosal melanoma. Surgical resection with postoperative radiotherapy plays a major role in managing resectable disease. Recent studies evaluate the addition of targeted, and immunotherapies with an attempt to determine the most efficacious sequence of treatment.

Keywords: Mucosal melanoma; Sinonasal melanoma.

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References

Bibliography

Papers of particular interest, published recently, have been highlighted as: • Of importance
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    1. Christopherson K, Malyapa RS, Werning JW, Morris CG, Kirwan J, Mendenhall WM. Radiation therapy for mucosal melanoma of the head and neck. Am J Clin Oncol. 2015;38(1):87–9. https://doi.org/10.1097/COC.0b013e31828d73bf . - DOI - PubMed
    1. Seetharamu N, Ott PA, Pavlick AC. Mucosal melanomas: a casebased review of the literature. Oncologist. 2010;15:772–81. - DOI - PubMed - PMC
    1. Papaspyrou G, Garbe C, Schadendorf D, et al. Mucosal melanomas of the head and neck: new aspects of the clinical outcome, molecular pathology, and treatment with c-kit inhibitors. Melanoma Res. 2011;21:475–82. - DOI - PubMed
    1. Edge SB American Joint Committee on Cancer. Ajcc Cancer Staging Manual 8th Ed. 8th ed. New York: Springer; 2017.

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