Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

doi:10.1016/j.virs.2024.03.006

Case Reports

. 2024 Jun;39(3):513-515.

doi: 10.1016/j.virs.2024.03.006. Epub 2024 Mar 20.

Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

Shuo Zhang¹, Yu Leng², Fa-Xue Zhang³, Bo-Kang Fu⁴, Bing-Zheng Wu², Jia-Hao Chen², Ning Cui⁵, Ning Zhao⁶, Wei Liu⁷, Hao Li⁸

Affiliations

¹ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China.
² State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China.
³ School of Public Health, Wuhan University, Wuhan, 430071, China.
⁴ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
⁵ Xinyang 154 Hospital, Xinyang, 464000, China.
⁶ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China. Electronic address: lijiangzhaon@swfu.edu.cn.
⁷ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. Electronic address: liuwei@bmi.ac.cn.
⁸ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; School of Public Health, Wuhan University, Wuhan, 430071, China. Electronic address: lihao_1986@126.com.

PMID: 38513807
PMCID: PMC11279768
DOI: 10.1016/j.virs.2024.03.006

Case Reports

Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

Shuo Zhang et al. Virol Sin. 2024 Jun.

. 2024 Jun;39(3):513-515.

doi: 10.1016/j.virs.2024.03.006. Epub 2024 Mar 20.

Authors

Shuo Zhang¹, Yu Leng², Fa-Xue Zhang³, Bo-Kang Fu⁴, Bing-Zheng Wu², Jia-Hao Chen², Ning Cui⁵, Ning Zhao⁶, Wei Liu⁷, Hao Li⁸

Affiliations

¹ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China.
² State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China.
³ School of Public Health, Wuhan University, Wuhan, 430071, China.
⁴ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
⁵ Xinyang 154 Hospital, Xinyang, 464000, China.
⁶ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China. Electronic address: lijiangzhaon@swfu.edu.cn.
⁷ College of Life Sciences, Southwest Forestry University, Kunming, 650224, China; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. Electronic address: liuwei@bmi.ac.cn.
⁸ State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing Key Laboratory of Vector Borne and Natural Focus Infectious Diseases, Beijing, 100071, China; School of Public Health, Wuhan University, Wuhan, 430071, China. Electronic address: lihao_1986@126.com.

PMID: 38513807
PMCID: PMC11279768
DOI: 10.1016/j.virs.2024.03.006

Abstract

•
SFTSV is detected in host-seeking ticks in rural–urban fringe areas in Beijing.
•
SFTSV RNA, IgM, and neutralizing antibodies are detected in stray cats in Beijing.
•
Multiple SFTSV genotypes naturally circulate within ticks in Beijing's urban zones.

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Figures

**Figure 1**
Detection of SFTSV in urbanized areas in Beijing. A The location where the patient acquired SFTSV infection, indicated by red triangle. B Five sites (S1 to S5) from where tick and cat samples were collected. Cats were living in site 1 (S1). Host-seeking ticks were collected by dragging fabric over vegetation at five sites. Blood-sucking ticks were collected from goats at site 1 (S1) and site 5 (S5). The red triangle indicates the location of the patient. The dotted box indicates the area size of the field survey (200 m∗200 m). C The positive rate of SFTSV in host-seeking or blood-sucking ticks. Host-seeking ticks were pooled (4–5 ticks per pool) for the detection of SFTSV RNA. The blood-sucking ticks collected from goats were individually tested. D Phylogenetic tree was conducted based on nucleotide sequence of nearly complete S segment (1743 bp) of SFTSV with Neighbor-Joining method and 1000 bootstrap replicate using MEGA X software. Corresponding nucleotide sequence of Heartland virus (GenBank accession number JX005842) was used as outgroup. Sequences obtained in this study were indicated as black triangle, with GenBank accession numbers of OR871539 (patient), OR871540 (cat), OR871541 and OR871542 (tick).

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References

1. Hwang J., Kang J.G., Oh S.S., Chae J.B., Cho Y.K., Cho Y.S., Lee H., Chae J.S. Molecular detection of severe fever with thrombocytopenia syndrome virus (SFTSV) in feral cats from Seoul, Korea. Ticks Tick Borne Dis. 2017;8:9–12. - PubMed
1. Kida K., Matsuoka Y., Shimoda T., Matsuoka H., Yamada H., Saito T., Imataki O., Kadowaki N., Noguchi K., Maeda K., Mochizuki Y., Kishimoto T. A case of cat-to-human transmission of severe fever with thrombocytopenia syndrome virus. Jpn. J. Infect. Dis. 2019;72:356–358. - PubMed
1. Kim K.H., Yi J., Kim G., Choi S.J., Jun K.I., Kim N.H., Choe P.G., Kim N.J., Lee J.K., Oh M.D. Severe fever with thrombocytopenia syndrome, South Korea, 2012. Emerg. Infect. Dis. 2013;19:1892–1894. - PMC - PubMed
1. Kim Y.R., Yun Y., Bae S.G., Park D., Kim S., Lee J.M., Cho N.H., Kim Y.S., Lee K.H. Severe fever with thrombocytopenia syndrome, South Korea, 2010. Emerg. Infect. Dis. 2018;24:2103–2105. - PMC - PubMed
1. Li H., Lu Q.B., Xing B., Zhang S.F., Liu K., Du J., Li X.K., Cui N., Yang Z.D., Wang L.Y., Hu J.G., Cao W.C., Liu W. Epidemiological and clinical features of laboratory-diagnosed severe fever with thrombocytopenia syndrome in China, 2011–17: a prospective observational study. Lancet Infect. Dis. 2018;18:1127–1137. - PubMed

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[1] Hwang J., Kang J.G., Oh S.S., Chae J.B., Cho Y.K., Cho Y.S., Lee H., Chae J.S. Molecular detection of severe fever with thrombocytopenia syndrome virus (SFTSV) in feral cats from Seoul, Korea. Ticks Tick Borne Dis. 2017;8:9–12. - PubMed

[2] Hwang J., Kang J.G., Oh S.S., Chae J.B., Cho Y.K., Cho Y.S., Lee H., Chae J.S. Molecular detection of severe fever with thrombocytopenia syndrome virus (SFTSV) in feral cats from Seoul, Korea. Ticks Tick Borne Dis. 2017;8:9–12. - PubMed

[3] Kida K., Matsuoka Y., Shimoda T., Matsuoka H., Yamada H., Saito T., Imataki O., Kadowaki N., Noguchi K., Maeda K., Mochizuki Y., Kishimoto T. A case of cat-to-human transmission of severe fever with thrombocytopenia syndrome virus. Jpn. J. Infect. Dis. 2019;72:356–358. - PubMed

[4] Kida K., Matsuoka Y., Shimoda T., Matsuoka H., Yamada H., Saito T., Imataki O., Kadowaki N., Noguchi K., Maeda K., Mochizuki Y., Kishimoto T. A case of cat-to-human transmission of severe fever with thrombocytopenia syndrome virus. Jpn. J. Infect. Dis. 2019;72:356–358. - PubMed

[5] Kim K.H., Yi J., Kim G., Choi S.J., Jun K.I., Kim N.H., Choe P.G., Kim N.J., Lee J.K., Oh M.D. Severe fever with thrombocytopenia syndrome, South Korea, 2012. Emerg. Infect. Dis. 2013;19:1892–1894. - PMC - PubMed

[6] Kim K.H., Yi J., Kim G., Choi S.J., Jun K.I., Kim N.H., Choe P.G., Kim N.J., Lee J.K., Oh M.D. Severe fever with thrombocytopenia syndrome, South Korea, 2012. Emerg. Infect. Dis. 2013;19:1892–1894. - PMC - PubMed

[7] Kim Y.R., Yun Y., Bae S.G., Park D., Kim S., Lee J.M., Cho N.H., Kim Y.S., Lee K.H. Severe fever with thrombocytopenia syndrome, South Korea, 2010. Emerg. Infect. Dis. 2018;24:2103–2105. - PMC - PubMed

[8] Kim Y.R., Yun Y., Bae S.G., Park D., Kim S., Lee J.M., Cho N.H., Kim Y.S., Lee K.H. Severe fever with thrombocytopenia syndrome, South Korea, 2010. Emerg. Infect. Dis. 2018;24:2103–2105. - PMC - PubMed

[9] Li H., Lu Q.B., Xing B., Zhang S.F., Liu K., Du J., Li X.K., Cui N., Yang Z.D., Wang L.Y., Hu J.G., Cao W.C., Liu W. Epidemiological and clinical features of laboratory-diagnosed severe fever with thrombocytopenia syndrome in China, 2011–17: a prospective observational study. Lancet Infect. Dis. 2018;18:1127–1137. - PubMed

[10] Li H., Lu Q.B., Xing B., Zhang S.F., Liu K., Du J., Li X.K., Cui N., Yang Z.D., Wang L.Y., Hu J.G., Cao W.C., Liu W. Epidemiological and clinical features of laboratory-diagnosed severe fever with thrombocytopenia syndrome in China, 2011–17: a prospective observational study. Lancet Infect. Dis. 2018;18:1127–1137. - PubMed

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Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

Affiliations

Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

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