Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Apr:117:109559.
doi: 10.1016/j.ijscr.2024.109559. Epub 2024 Mar 19.

Endoscopic treatement by vaginoscopy of a Herlyn-Werner-Wunderlich syndrome: A case report

Farah Flissate  1 , Hounaida Mahfoud  2 , Youssef Essebagh  2 , Najia Zeraidi  2 , Amina Lakhdar  2 , Aziz Baidada  2
Affiliations
Case Reports

Endoscopic treatement by vaginoscopy of a Herlyn-Werner-Wunderlich syndrome: A case report

Farah Flissate et al. Int J Surg Case Rep. 2024 Apr.

Abstract

Introduction: Herlyn-Werner-Wunderlich syndrome is a rare complex congenital disorder, presenting with obstructed vagina, uterus didelphys and ipsilateral renal agenesis. Hemivaginal obstruction firstly asymptomatic, leads to symptoms after menarche such as dysmenorrhea, pelvic pain or infertility.

Case presentation: A 15-year-old patient presenting with few symptoms, transvaginal ultrasound reveals an hematocolpos, we report also typical findings of this disorder on magnetic resonance imaging.

Discussion: The pelvic pain caused by the hematocolpos is the main symptom that leads patients to consult often urgently, the MRI is the gold standard exam to confirm diagnosis, the treatment consists on incision the septum vaginal and leads to avoid complications.

Conclusion: Early diagnosis of this syndrome usually leads to initiate surgical treatment in order to avoid complications.

Keywords: Hematocolpos; Herlyn-Werner-Wunderlich syndrome; Obstructed vagina; Pelvic pain; Septum excision.; Vaginoscopy.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare that they have no competing interests relevant to the content of this article.

Figures

Fig. 1
Fig. 1
coronal section of IRM showing left renal agenisis.
Fig. 2
Fig. 2
an axial cross-section of IRM showing the agenisis of the left kidney.
Fig. 3
Fig. 3
a coronal section of IRM showing a uterus didelphys a left hematometra and a left Hematocolpos.
Fig. 4
Fig. 4
an image of the Vaginoscopy procedure after resection of the vaginal septum showing 2 hemivaginas.
Fig. 5
Fig. 5
an image of ultrasound showing the uterus didelphys 3 months after surgery.
Fig. 6
Fig. 6
classification of the Herlyn-Werner-Wunderlich.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. C. E. Purslow, «A case of unilateral hæmatokolpos, hæmatometra and hæmatosalpinx. », BJOG Int. J. Obstet. Gynaecol., vol. 29, no 4, p. 643–643, déc. 1922, doi:10.1111/j.1471-0528.1922.tb16100.x. - DOI
    1. J. P. Stassart, T. C. Nagel, K. A. Prem, W. R. Phipps, « Uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis: the University of Minnesota experience », Fertil. Steril., vol. 57, no 4, p. 756–761, avr. 1992, doi:10.1016/s0015-0282(16)54955-3. - DOI - PubMed
    1. B. Patil, R. M. Nagaraju, « Uterine didelphys with obstructed hemivagina and ipsilateral renal anomaly - OHVIRA syndrome: a rare congenital anomaly », Int. J. Reprod. Contracept. Obstet. Gynecol., vol. 4, no 3, p. 889–892, 2015, doi: 10.18203/2320-1770.ijrcog20150121. - DOI
    1. Del Vescovo R., et al. Herlyn-Werner-Wunderlich syndrome: MRI findings, radiological guide (two cases and literature review), and differential diagnosis. BMC Med. Imaging. mars 2012;12:4. doi: 10.1186/1471-2342-12-4. - DOI - PMC - PubMed
    1. O. O. Gutiérrez-Montufar, C. P. Zambrano-Moncayo, M. C. Otálora-Gallego, A. L. Meneses-Parra, I. Díaz-Yamal, « Herlyn-Werner-Wunderlich syndromne: case review and report of the literature », Rev. Colomb. Obstet. Ginecol., vol. 72, no 4, p. 407–422, déc. 2021, doi: 10.18597/rcog.3699. - DOI - PMC - PubMed

Publication types