Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Mar 8:4:1254294.
doi: 10.3389/frhs.2024.1254294. eCollection 2024.

Addressing disparities in cancer clinical trials: a roadmap to more equitable accrual

Affiliations

Addressing disparities in cancer clinical trials: a roadmap to more equitable accrual

Jon A Hoin et al. Front Health Serv. .

Abstract

The Georgia Center for Oncology Research and Education (Georgia CORE) and the Georgia Society of Clinical Oncology (GASCO) held a one-day summit exploring opportunities and evidence-based interventions to address disparities in cancer clinical trials. The purpose of the summit was to identify clear and concise recommendations aimed at decreasing clinical trial accrual disparities in Georgia for rural and minority populations. The summit included expert presentations, panel discussions with leaders from provider organizations throughout Georgia, and breakout sessions to allow participants to critically discuss the information presented. Over 120 participants attended the summit. Recognizing the need for evidence-based interventions to improve clinical trial accrual among rural Georgians and persons of color, summit participants identified four key areas of focus that included: improving clinical trial design, providing navigation for all, enhancing public education and awareness of cancer clinical trials, and identifying potential policy and other opportunities. A comprehensive list of takeaways and action plans was developed in the four key areas of focus with the expectation that implementation of the strategies that emerged from the summit will enhance cancer clinical trial accrual for all Georgians.

Keywords: cancer care access; clinical trial accrual; clinical trials; disparities; navigation.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Oyer RA, Hurley P, Boehmer L, Bruinooge SS, Levit K, Barrett N, et al. Increasing racial and ethnic diversity in cancer clinical trials: an American society of clinical oncology and association of community cancer centers joint research statement. J Clin Oncol. (2022) 40(19):2163–71. 10.1200/JCO.22.00754 - DOI - PubMed
    1. Duma N, Vera Aguilera J, Paludo J, Haddox CL, Gonzalez Velez M, Wang Y, et al. Representation of minorities and women in oncology clinical trials: review of the past 14 years. J Oncol Pract. (2018) 14(1):e1–e10. 10.1200/JOP.2017.025288 - DOI - PubMed
    1. Unger JM, Vaidya R, Hershman DL, Minasian LM, Fleury ME. Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation. JNCI J Natl Cancer Inst. (2019) 111(3):245–55. 10.1093/jnci/djy221 - DOI - PMC - PubMed
    1. Eskander MF, Gil L, Beal EW, Li Y, Hamad A, Oppong B, et al. Access denied: inequities in clinical trial enrollment for pancreatic cancer. Ann Surg Oncol. (2022) 29(2):1271–7. 10.1245/s10434-021-10868-4 - DOI - PubMed
    1. Brundage MD. Revisiting barriers to clinical trials accrual. JNCI J Natl Cancer Inst. (2021) 113(3):219–20. 10.1093/jnci/djaa156 - DOI - PMC - PubMed

LinkOut - more resources