Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Mar 18:17:123-133.
doi: 10.2147/MDER.S454849. eCollection 2024.

Usefulness of Non-Invasive Parameters (Inferior Vena Cava Diameter, Inferior Vena Cava Collapsibility, Inferior Vena Cava-Aortic Ratio) for Hemodynamic Monitoring in Critically Ill Children: A Systematic Review

Dzulfikar Djalil Lukman Hakim #  1 , Fina Meilyana #  1 , Stanza Uga Peryoga #  1 , Irma Arniawati #  1 , Elrika Anastasia Wijaya #  1 , Muhamad Rinaldhi Martiano #  1
Affiliations
Review

Usefulness of Non-Invasive Parameters (Inferior Vena Cava Diameter, Inferior Vena Cava Collapsibility, Inferior Vena Cava-Aortic Ratio) for Hemodynamic Monitoring in Critically Ill Children: A Systematic Review

Dzulfikar Djalil Lukman Hakim et al. Med Devices (Auckl). .

Abstract

Purpose: Volume measurement in critically ill children can be conducted using invasive procedure such as Central Venous Pressure (CVP), or non-invasive procedure such as measurement of Inferior Vena Cava (IVC) indices using ultrasonography. However, their accuracy and efficacy are still under scrutiny. We aim to compare CVP and IVC indices as non-invasive parameters in assessing volume status in critically ill children.

Methods: We conducted a systematic review based on literature searching from four electronic databases which were PubMed, Cochrane, ScienceDirect, SpringerLink with keywords: "CENTRAL VENOUS PRESSURE", "INFERIOR VENA CAVA DIAMETER", "INFERIOR VENA CAVA COLLAPSIBILITY", "INFERIOR VENA CAVA AORTIC-RATIO", "VOLUME STATUS", "FLUID STATUS", "CRITICAL ILL", "CHILDREN", and "PEDIATRICS". We included relevant studies in English published from 2000 to 2023 on critically ill children aged 0-18 years. Comparison between CVP and IVC indices was resumed.

Results: Eight articles were included in this study. Majority of the studies showed a consistent correlation between CVP and IVC indices. IVC-CI was the most common parameter evaluated in the included studies. There was moderate to strong correlations using IVC-CI and IVC-DI, and moderate correlation using IVC-Ao ratio.

Conclusion: We found that non-invasive tools might have a potential role to measure volume in critically ill children equals to CVP. Further high-quality and longitudinal studies are needed to validate these findings and to establish a clear guideline for the non-invasive tool to be used in daily clinical practice.

Keywords: critically ill children; hemodynamic monitoring; non-invasive parameter; pediatric intensive care; ultrasonography.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Article Search and Selection Flowchart.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Assies R, Snik I, Kumwenda M, et al. Etiology, pathophysiology and mortality of shock in children in low (middle) income countries: a systematic review. J Trop Pediatr. 2022;68(4):fmac053. doi:10.1093/tropej/fmac053 - DOI - PMC - PubMed
    1. Gui J, Guo J, Nong F, et al. Impact of individual characteristics on sonographic IVC diameter and the IVC diameter/aorta diameter index. Am J Emerg Med. 2015;33(11):1602–1605. doi:10.1016/j.ajem.2015.06.047 - DOI - PubMed
    1. Elbaih AH, Safi MR. Approach to critical ill child. Medicine. 2021;10(1):1.
    1. Airapetian N, Maizel J, Alyamani O, et al. Does inferior vena cava respiratory variability predict fluid responsiveness in spontaneously breathing patients? Crit Care. 2015;19(1):1–8. doi:10.1186/s13054-015-1100-9 - DOI - PMC - PubMed
    1. Kusumastuti NP, Latief A, Pudjiadi AH. Inferior vena cava/abdominal aorta ratio as a guide for fluid resuscitation. J Emerg Trauma Shock. 2021;14(4):211. doi:10.4103/JETS.JETS_154_20 - DOI - PMC - PubMed