Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives

doi:10.3389/fnins.2024.1361832

Review

. 2024 Mar 11:18:1361832.

doi: 10.3389/fnins.2024.1361832. eCollection 2024.

Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives

Tao Liu^#^{1

2

3}, Shaohui Yu^#^{1

2}, Mingqi Liu^#^{1

2}, Zhihao Zhao^{1

2}, Jiangyuan Yuan^{1

2}, Zhuang Sha^{1

2}, Xuanhui Liu^{1

2}, Yu Qian^{1

2}, Meng Nie^{1

2}, Rongcai Jiang^{1

2}

Affiliations

¹ Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
² Tianjin Neurological Institute, Key Laboratory of Post Neuro-Injury Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.
³ The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.

^# Contributed equally.

PMID: 38529265
PMCID: PMC10961372
DOI: 10.3389/fnins.2024.1361832

Review

Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives

Tao Liu et al. Front Neurosci. 2024.

. 2024 Mar 11:18:1361832.

doi: 10.3389/fnins.2024.1361832. eCollection 2024.

Authors

Tao Liu^#^{1

2

3}, Shaohui Yu^#^{1

2}, Mingqi Liu^#^{1

2}, Zhihao Zhao^{1

2}, Jiangyuan Yuan^{1

2}, Zhuang Sha^{1

2}, Xuanhui Liu^{1

2}, Yu Qian^{1

2}, Meng Nie^{1

2}, Rongcai Jiang^{1

2}

Affiliations

¹ Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
² Tianjin Neurological Institute, Key Laboratory of Post Neuro-Injury Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.
³ The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.

^# Contributed equally.

PMID: 38529265
PMCID: PMC10961372
DOI: 10.3389/fnins.2024.1361832

Abstract

Traumatic Brain Injury (TBI) is a prevalent form of neurological damage that may induce varying degrees of cognitive dysfunction in patients, consequently impacting their quality of life and social functioning. This article provides a mini review of the epidemiology in Chinese TBI patients and etiology of cognitive impairment. It analyzes the risk factors of cognitive impairment, discusses current management strategies for cognitive dysfunction in Chinese TBI patients, and summarizes the strengths and limitations of primary testing tools for TBI-related cognitive functions. Furthermore, the article offers a prospective analysis of future challenges and opportunities. Its objective is to contribute as a reference for the prevention and management of cognitive dysfunction in Chinese TBI patients.

Keywords: challenges; cognitive impairment; dysfunction; epidemiology; opportunities; risk factors; traumatic brain injury.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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References

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1. Bayley M. T., Janzen S., Harnett A., Teasell R., Patsakos E., Marshall S., et al. (2023). INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury: Methods, overview, and principles. J. Head Trauma Rehabil. 38 7–23. 10.1097/htr.0000000000000838 - DOI - PubMed
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[1] Almomani F., Avi-Itzhak T., Demeter N., Josman N., Al-Momani M. O. (2018). Construct validity and internal consistency reliability of the Loewenstein occupational therapy cognitive assessment (LOTCA). BMC Psychiatry 18:184. 10.1186/s12888-018-1776-x - DOI - PMC - PubMed

[2] Almomani F., Avi-Itzhak T., Demeter N., Josman N., Al-Momani M. O. (2018). Construct validity and internal consistency reliability of the Loewenstein occupational therapy cognitive assessment (LOTCA). BMC Psychiatry 18:184. 10.1186/s12888-018-1776-x - DOI - PMC - PubMed

[3] Amantini A., Grippo A., Fossi S., Cesaretti C., Piccioli A., Peris A., et al. (2005). Prediction of ‘awakening’ and outcome in prolonged acute coma from severe traumatic brain injury: Evidence for validity of short latency SEPs. Clin. Neurophysiol. 116 229–235. 10.1016/j.clinph.2004.07.008 - DOI - PubMed

[4] Amantini A., Grippo A., Fossi S., Cesaretti C., Piccioli A., Peris A., et al. (2005). Prediction of ‘awakening’ and outcome in prolonged acute coma from severe traumatic brain injury: Evidence for validity of short latency SEPs. Clin. Neurophysiol. 116 229–235. 10.1016/j.clinph.2004.07.008 - DOI - PubMed

[5] Antila S., Karaman S., Nurmi H., Airavaara M., Voutilainen M. H., Mathivet T., et al. (2017). Development and plasticity of meningeal lymphatic vessels. J. Exp/Med. 214 3645–3667. 10.1084/jem.20170391 - DOI - PMC - PubMed

[6] Antila S., Karaman S., Nurmi H., Airavaara M., Voutilainen M. H., Mathivet T., et al. (2017). Development and plasticity of meningeal lymphatic vessels. J. Exp/Med. 214 3645–3667. 10.1084/jem.20170391 - DOI - PMC - PubMed

[7] Bayley M. T., Janzen S., Harnett A., Teasell R., Patsakos E., Marshall S., et al. (2023). INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury: Methods, overview, and principles. J. Head Trauma Rehabil. 38 7–23. 10.1097/htr.0000000000000838 - DOI - PubMed

[8] Bayley M. T., Janzen S., Harnett A., Teasell R., Patsakos E., Marshall S., et al. (2023). INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury: Methods, overview, and principles. J. Head Trauma Rehabil. 38 7–23. 10.1097/htr.0000000000000838 - DOI - PubMed

[9] Bolte A. C., Dutta A. B., Hurt M. E., Smirnov I., Kovacs M. A., McKee C. A., et al. (2020). Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nat. Commun. 11:4524. 10.1038/s41467-020-18113-4 - DOI - PMC - PubMed

[10] Bolte A. C., Dutta A. B., Hurt M. E., Smirnov I., Kovacs M. A., McKee C. A., et al. (2020). Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nat. Commun. 11:4524. 10.1038/s41467-020-18113-4 - DOI - PMC - PubMed

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Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives

Affiliations

Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives

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Conflict of interest statement

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Abstract

Conflict of interest statement

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