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Comment
. 2024 Mar 1;15(3):e00654.
doi: 10.14309/ctg.0000000000000654.

Rapid HBsAg Decline Can Predict HBsAg Seroclearance Only in Patients With HBsAg <200 IU/mL

Yi-Cheng Chen  1   2   3 , Yun-Fan Liaw  1   2
Affiliations
Comment

Rapid HBsAg Decline Can Predict HBsAg Seroclearance Only in Patients With HBsAg <200 IU/mL

Yi-Cheng Chen et al. Clin Transl Gastroenterol. .
No abstract available

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Conflict of interest statement

Guarantor of the article: Yun-Fan Liaw, MD.

Specific author contributions: Y.-C.C. and Y.-F.L.: contributed equally.

Financial support: The authors were supported by grants from Chang Gung Medical Research Fund (CMRPG1K0101-3, CMRPG1K0111-3) and the Prosperous Foundation, Taipei, Taiwan.

Potential competing interests: None to report.

Comment in

  • Response to Chen and Liaw.
    Lin HC, Jeng WJ, Yang HI. Lin HC, et al. Clin Transl Gastroenterol. 2024 Mar 1;15(3):e00663. doi: 10.14309/ctg.0000000000000663. Clin Transl Gastroenterol. 2024. PMID: 38529916 Free PMC article. No abstract available.

Comment on

References

    1. Lin HC, Liu J, Pan MH, et al. Rapid decline rather than absolute level of HBsAg predicts its seroclearance in untreated chronic hepatitis B patients from Taiwanese communities. Clin Transl Gastroenterol 2023;14:e00586. - PMC - PubMed
    1. Chen YC, Jeng WJ, Chu CM, et al. Decreasing levels of HBsAg predict HBsAg seroclearance in patients with inactive chronic hepatitis B virus infection. Clin Gastroenterol Hepatol 2012;10:297–302. - PubMed
    1. Seto WK, Wong DK, Fung J, et al. A large case-control study on the predictability of hepatitis B surface antigen levels three years before hepatitis B surface antigen seroclearnce. Hepatology 2012;56:812–9. - PubMed
    1. Jeng WJ, Chang ML, Liaw YF. Off-therapy precipitous HBsAg decline predicts HBsAg loss after finite entecavir therapy in HBeAg-negative patients. J Viral Hepat 2019;26:1019–26. - PubMed

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