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. 2024 Mar 25;11(Suppl 1):S113-S120.
doi: 10.1093/ofid/ofad651. eCollection 2024 Mar.

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Pakistan

Naveed Ahmed  1 , Mohammad Tahir Yousafzai  1 , Farah Naz Qamar  1
Affiliations

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Pakistan

Naveed Ahmed et al. Open Forum Infect Dis. .

Abstract

Background: The Enterics for Global Health (EFGH) Shigella surveillance study is a longitudinal multicountry study that aims to estimate incidence rates and document consequences of Shigella diarrhea within 7 countries in Africa, Asia, and Latin America. In addition to a high incidence of childhood diarrhea, Pakistan is facing a problem of antimicrobial resistance in urban and peri-urban areas of Karachi.

Methods: In Pakistan, EFGH will be conducted in Karachi, which is one of the metropolitan cities bordering the Arabian Sea and has a diverse population of 1.6 million according to the 2017 population census. The study aims to enroll 1400 children aged 6-35 months over 2 years (2022-2024) from 6 health care facilities (Abbasi Shaheed Hospital, Khidmat-e-Alam Medical Centre, Sindh Government Hospital Korangi 5, Sindh Government Hospital Ibrahim Hyderi, Ali Akbar Shah VPT Center, and Bhains Colony VPT Center) situated in Nazimabad and Bin-Qasim town. Moreover, population enumeration and health care utilization surveys from a defined catchment area of health facilities will be conducted to estimate the Shigella diarrhea incidence rates.

Conclusions: The study will provide critical data to policy-makers about the burden of Shigella and antimicrobial resistance, which is essential for planning Shigella vaccine trials.

Keywords: Karachi; Pakistan; Shigella; surveillance.

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Conflict of interest statement

Potential conflicts of interest. All authors: no reported conflicts.

Figures

Figure 1.
Figure 1.
Study catchment area and surveillance sites.
See this image and copyright information in PMC

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