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. 2024 Mar 25;11(Suppl 1):S76-S83.
doi: 10.1093/ofid/ofad653. eCollection 2024 Mar.

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Bangladesh

Farhana Khanam  1 , Md Taufiqul Islam  1 , Taufiqur Rahman Bhuiyan  1 , Md Ismail Hossen  1 , Md Nazmul Hasan Rajib  1 , Shahinur Haque  1 , Mahzabeen Ireen  1 , Syed Qudrat-E-Khuda  1 , Prasanta Kumar Biswas  1 , Md Amirul Islam Bhuiyan  1 , Kamrul Islam  1 , Nazia Rahman  1 , S M Azadul Alam Raz  1 , Md Parvej Mosharraf  1 , Md Elias Shawon Bhuiyan  1 , Sadia Islam  1 , Dilruba Ahmed  1 , Faisal Ahmmed  1 , Khalequ Zaman  1 , John D Clemens  2   3 , Firdausi Qadri  1
Affiliations

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Bangladesh

Farhana Khanam et al. Open Forum Infect Dis. .

Abstract

Background: Shigella is an important cause of diarrhea in Bangladeshi children <5 years of age, with an incidence rate of 4.6 per 100 person-years. However, the report was more than a decade old, and data on Shigella consequences are similarly outdated and heterogeneously collected.

Methods: Facility-based disease surveillance is planned to be carried out under the Enterics for Global Health (EFGH) Shigella Surveillance Study consortium for 2 years with aims to optimize and standardize laboratory techniques and healthcare utilization and coverage survey, clinical and anthropometric data collection, safety monitoring and responsiveness, and other related activities. The EFGH is a cohesive network of multidisciplinary experts, capable of operating in concert to conduct the study to generate data that will pave the way for potential Shigella vaccine trials in settings with high disease burden. The study will be conducted within 7 country sites in Asia, Africa, and Latin America.

Conclusions: We outline the features of the Bangladesh site as part of this multisite surveillance network to determine an updated incidence rate and document the consequences of Shigella diarrhea in children aged 6-35 months, which will help inform policymakers and to implement the future vaccine trials.

Keywords: Bangladesh; Shigella burden; disease surveillance.

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Conflict of interest statement

Potential conflicts of interest. All authors: No reported conflicts.

Figures

Figure 1.
Figure 1.
Map of Enterics for Global Health (EFGH) catchment area and healthcare facilities of the Bangladesh site. We have prepared the figures by using the licensed version of the Software ArcGIS10.8.1 (ESRI Inc.) Background map: esri open source map, Bangladesh map: Humanitarian data exchange (HDX)admin map.
See this image and copyright information in PMC

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