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Comparative Study
. 2024 Jun;35(6):1115-1120.
doi: 10.1111/jce.16255. Epub 2024 Mar 27.

Feasibility of a novel atrial mechanical sensing method for leadless atrioventricular synchronous pacing

Shuichiro Kazawa  1 , Chifumi Kazawa  1 , Tomoko Sakaida  2 , Hidetaka Murakami  1 , Yasuyuki Takada  1 , Takahiro Kusume  2 , Muryo Terasawa  2 , Nobuhiro Tanaka  1 , Kazuhiro Satomi  2 , Yoshinao Yazaki  2
Affiliations
Comparative Study

Feasibility of a novel atrial mechanical sensing method for leadless atrioventricular synchronous pacing

Shuichiro Kazawa et al. J Cardiovasc Electrophysiol. 2024 Jun.

Abstract

Introduction: Few studies have demonstrated a high degree of atrioventricular (AV) synchrony with a new leadless pacemaker called Micra AV. Our group previously reported a new and unique sensing method. We believe that this novel sensing method, "Simplified A3 method," might facilitate better AV synchrony than a conventional sensing method in almost all cases with Micra AV implantation.

Methods: We conducted a non-randomized retrospective study comparing the two pacing methods at two centers. From December 1, 2021 to October 31, 2022, Micra AV was implanted for 32 patients at the two centers. Twenty of the 32 patients with sinus rhythm and complete AV block were included in this study. In Group 1, the conventional setting was programmed as follows: auto A3 threshold, auto A3 window-end (WE), and auto A4 threshold turned on during hospitalization. In Group 2, the "Simplified A3 method" was programmed as follows: auto A3 threshold and auto A3WE turned off. Instead, an intentionally prolonged A3WE (850-1000 ms) and low A3 threshold (A3 signal amplitude + 0.5-1.0 m/s2) were programmed.

Results: Twenty patients were analyzed. In Group 2, AV synchrony (%AMVp) was significantly higher at the first outpatient clinic (63.0 ± 5.7% vs 81.0 ± 4.2%, p = .03). A3 threshold was significantly lower in Group 2 (5.9 ± 0.7 m/s2, p < .05 vs 2.3 ± 0.5 m/s2, p < .05).

Conclusion: Our novel sensing method might be a more feasible sensing method for obtaining higher AV synchrony than the conventional algorithm.

Keywords: Micra AV; atrial sensing; atrioventricular block; atrioventricular synchronous pacing; leadless pacemaker.

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References

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