Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jul;35(4):444-453.
doi: 10.1111/cyt.13378. Epub 2024 Mar 27.

Interobserver variability in cytopathology: How much do we agree?

Gennaro Acanfora  1 , Anna Maria Carillo  1 , Filippo Dello Iacovo  1 , Maria Salatiello  1 , Pasquale Pisapia  1 , Claudio Bellevicine  1 , Giancarlo Troncone  1 , Elena Vigliar  1
Affiliations
Review

Interobserver variability in cytopathology: How much do we agree?

Gennaro Acanfora et al. Cytopathology. 2024 Jul.

Abstract

Interobserver variability remains a major challenge for cytopathologists despite the development of standardized reporting and classification systems. Indeed, whereas moderate-to-good interobserver agreement is generally achievable when the differential diagnosis between benign and malignant entities is straightforward, high levels of variability make the diagnostic interpretation of atypical and suspicious samples not consistent. This review explores the landscape of interobserver agreement in cytopathology across different anatomical sites.

Keywords: cytology; interobserver; salivary gland; salivary gland cytology; thyroid cytology; variability.

PubMed Disclaimer

References

REFERENCES

    1. Cibas ES. We are minimally invasive diagnosis. J Am Soc Cytopathol. 2021;10(2):113‐114.
    1. Monaco SE. Fine needle aspiration cytology. In: McManus LM, Mitchell RN, eds. Pathobiology of Human Disease. Academic Press; 2014:3379‐3398.
    1. Pitman MB, Black‐Schaffer WS. Post‐fine‐needle aspiration biopsy communication and the integrated and standardized cytopathology report. Cancer Cytopathol. 2017;125(S6):486‐493.
    1. Nayar R, Wilbur DC, eds. The Bethesda System for Reporting Cervical Cytology: Definitions, Criteria, and Explanatory Notes. Springer International Publishing; 2015.
    1. Ali SZ, VanderLaan PA, eds. The Bethesda System for Reporting Thyroid Cytopathology: Definitions, Criteria, and Explanatory Notes. Springer International Publishing; 2023.

LinkOut - more resources