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Review
. 2024 May 1;62(5):467-472.
doi: 10.3760/cma.j.cn112139-20231020-00183.

[Application of computational fluid dynamics in the evaluation of left ventricular function in cardiomyopathies and coronary disease]

[Article in Chinese]
Affiliations
Review

[Application of computational fluid dynamics in the evaluation of left ventricular function in cardiomyopathies and coronary disease]

[Article in Chinese]
Y N Zhang et al. Zhonghua Wai Ke Za Zhi. .

Abstract

Computational fluid dynamics (CFD) is an emerging technology applied in the field of cardiovascular medicine, which can obtain hemodynamic data by simulating the blood flow in the patient's heart for cardiac function assessment and disease diagnosis. Left ventricular function plays a key role in the occurrence and development of cardiomyopathies and coronary disease. CFD can reconstruct the left ventricular anatomic structures of patients to clarify pathophysiologic mechanisms and analyze hemodynamic parameters to evaluate left ventricular function, verify surgical efficacy, and guide surgical strategy, which has a positive effect on achieving early diagnosis and reducing mortality from cardiomyopathies and coronary disease. At present, there are still technical limitations in the large-scale clinical application of CFD, and various solutions are being developed and tested, and further improvement and refinement are needed.

计算流体力学是应用于心血管医学领域的新兴技术,可通过模拟计算患者心脏内血液的流动,得到血流动力学数据,用于心脏功能评估和疾病辅助诊断。左心室功能在心肌病和冠心病的发生发展中起着关键作用。计算流体力学可通过重建患者左心室解剖构型明确病理生理学机制,分析血流动力学参数,评价左心室功能并验证手术疗效、指导手术方案,对实现心肌病和冠心病的早期诊断、降低病死率有积极作用。目前计算流体力学的大规模临床应用仍存在技术局限,各类解决方案正初步开发试用,尚需进一步完善。.

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