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Comment
. 2024 May;23(5):336.
doi: 10.1038/d41573-024-00055-x.

Kinase inhibitor rescues the liver

Sarah Crunkhorn
Comment

Kinase inhibitor rescues the liver

Sarah Crunkhorn. Nat Rev Drug Discov. 2024 May.
No abstract available

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Comment on

  • First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
    Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L. Zwirner S, et al. Cell. 2024 Mar 28;187(7):1666-1684.e26. doi: 10.1016/j.cell.2024.02.023. Epub 2024 Mar 14. Cell. 2024. PMID: 38490194 Free PMC article. Clinical Trial.

References

    1. Zwirner, S. et al. First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure. Cell https://doi.org/10.1016/j.cell.2024.02.023 (2024)

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