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. 2021 Apr 20:2:100008.
doi: 10.1016/j.ahjo.2021.100008. eCollection 2021 Feb.

Valvular fibroelastomas complicated by Coxiella burnetti endocarditis

Affiliations

Valvular fibroelastomas complicated by Coxiella burnetti endocarditis

Eyal Meltzer et al. Am Heart J Plus. .

Abstract

Cardiac papillary fibroelastoma (CPF) is a valvular tumor that may be mistaken for infective endocarditis (IE). We describe a case of CPF complicated by Coxiella burnetti IE. According to Duke's criteria, a diagnosis of IE was repeatedly considered as excluded or established during the clinical course, highlighting the criteria limitations.

Keywords: Coxiella burnetti; Endocarditis/diagnosis; Infective endocarditis; Papillary fibroelastoma; Primary cardiac tumor.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Cardiac papillary fibroelastoma: echocardiographic findings. Echocardiography findings: Transthoracic Apical 5-chamber view showing large vegetation-like lesions on the tricuspid (A), Aortic (B) and mitral (C) valves.
Fig. 3
Fig. 3
Cardiac papillary fibroelastoma: pathological findings. Histopathological findings: Hematoxylin & eosin[H&E] stained sections: A. (×40) A papillary mass showing numerous arborizing papillary fronds arising from a common central stalk continuous with that of the valve leaflet. B. (×100) The papillae consist of central cores of hyalinized stroma (*avascular, dense, fibrotic connective tissue, with almost acellular collagen). The fronds are coated by a single endothelial layer (arrows).

References

    1. Tamin S.S., Maleszewski J.J., Scott C.G., Khan S.K., Edwards W.D., Bruce C.J., Oh J.K., Pellikka P.A., Klarich K.W. Prognostic and bioepidemiologic implications of papillary fibroelastomas. J. Am. Coll. Cardiol. 2015;65:2420–2429. - PubMed
    1. Gowda R.M., Khan I.A., Nair C.K., Mehta N.J., Vasavada B.C., Sacchi T.J. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am. Heart J. 2003;146:404–410. - PubMed
    1. Ajiboye O., Racoma J.M., Hussain K., Mba B. Double valve involvement: papillary fibroelastoma in a patient with severe mitral and aortic valve regurgitation. BMJ Case Rep. 2020;13 - PMC - PubMed
    1. Raoult D., Tissot-Dupont H., Foucault C., Gouvernet J., Fournier P.E., Bernit E., Stein A., Nesri M., Harle J.R., Weiller P.J. Q fever 1985-1998. Clinical and epidemiologic features of 1,383 infections. Medicine. 2000;79:109–123. - PubMed
    1. Shapira N., Merin O., Rosenmann E., Dzigivker I., Bitran D., Yinnon A.M., Silberman S. Latent infective endocarditis: epidemiology and clinical characteristics of patients with unsuspected endocarditis detected after elective valve replacement. Ann. Thorac. Surg. 2004;78:1623–1629. - PubMed

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