Patients' values and preferences for health states in allergic rhinitis-An artificial intelligence supported systematic review

Jan Brozek^{1

2

3

4}, Ewa Borowiack⁴, Ewelina Sadowska⁴, Artur Nowak⁴, Bernardo Sousa-Pinto^{5

6}, Rafael José Vieira^{5

6}, Antonio Bognanni^{1

7}, Juan Jose Yepes Nuñez^{8

9}, Yuan Zhang¹, Torsten Zuberbier^{10

11

12}, Jean Bousquet^{10

11

12}, Holger J Schünemann^{1

2

3

13}

Affiliations

¹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
² Michael G. DeGroote Cochrane Canada & McMaster GRADE Centres, McMaster University, Hamilton, Ontario, Canada.
³ Department of Medicine, McMaster University, Hamilton, Canada.
⁴ Evidence Prime, Hamilton, Ontario, Canada.
⁵ Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Porto, Portugal.
⁶ Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal.
⁷ Department of Medicine, Evidence in Allergy Group, McMaster University, Hamilton, Canada.
⁸ School of Medicine, Universidad de los Andes, Bogotá, Colombia.
⁹ Fundación Santa Fe de Bogotá Hospital University, Bogotá, Colombia.
¹⁰ Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
¹¹ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
¹² Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Frankfurt/Main, Germany.
¹³ Clinical Epidemiology and Research Center (CERC), Humanitas University and Humanitas Research Hospital, Milan, Italy.

PMID: 38551028
DOI: 10.1111/all.16100

Patients' values and preferences for health states in allergic rhinitis-An artificial intelligence supported systematic review

Jan Brozek et al. Allergy. 2024 Jul.

. 2024 Jul;79(7):1812-1830.

doi: 10.1111/all.16100. Epub 2024 Mar 29.

Authors

Affiliations

¹ Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
² Michael G. DeGroote Cochrane Canada & McMaster GRADE Centres, McMaster University, Hamilton, Ontario, Canada.
³ Department of Medicine, McMaster University, Hamilton, Canada.
⁴ Evidence Prime, Hamilton, Ontario, Canada.
⁵ Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Porto, Portugal.
⁶ Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal.
⁷ Department of Medicine, Evidence in Allergy Group, McMaster University, Hamilton, Canada.
⁸ School of Medicine, Universidad de los Andes, Bogotá, Colombia.
⁹ Fundación Santa Fe de Bogotá Hospital University, Bogotá, Colombia.
¹⁰ Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
¹¹ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
¹² Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Frankfurt/Main, Germany.
¹³ Clinical Epidemiology and Research Center (CERC), Humanitas University and Humanitas Research Hospital, Milan, Italy.

PMID: 38551028
DOI: 10.1111/all.16100

Abstract

Background: Allergic rhinitis (AR) impacts patients' physical and emotional well-being. Assessing patients' values and preferences (V&P) related to AR is an essential part of patient-centered care and of the guideline development process. We aimed to systematically summarize the information about patients' V&P on AR and its symptoms and impact on daily life.

Methods: We conducted systematic review in a MEDLINE, Embase, PsychInfo, and CINAHL databases. We included studies which quantitatively assessed patients' V&P for specific outcomes in AR by assessing utilities, applying discrete choice approaches, or rating and ranking outcomes. We grouped outcomes as AR symptoms, functional status, and care-related patient experience. Study selection and data extraction were supported by the Laser AI tool. We rated the certainty of evidence (CoE) using the GRADE approach.

Results: Thirty-six studies (41 records) were included: nine utility studies, seven direct-choice studies and 21 studies of rating or ranking outcomes. Utilities were lower with increased AR severity and with the concomitant presence of asthma, but not with whether AR was seasonal or perennial (CoE = low-high). Patients rated AR symptom-related outcomes as more important than those related to care-related patient experience and functional status (CoE = very low-moderate). Nasal symptoms (mainly nasal congestion) followed by breathing disorders, general and ocular symptoms were rated as the symptoms with the highest impact.

Conclusions: This systematic review provides a comprehensive overview of V&P of patients with AR. Patients generally considered nasal symptoms as the most important. Future studies with standardized methods are needed to provide more information on V&P in AR.

Keywords: allergic rhinitis; health states; systematic review; utility; values and preferences.

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References

REFERENCES

1. Savouré M, Bousquet J, Jaakkola JJK, Jaakkola MS, Jacquemin B, Nadif R. Worldwide prevalence of rhinitis in adults: A review of definitions and temporal evolution. Clin Transl Allergy. 2022;12(3):e12130.
1. Bousquet J, Anto JM, Bachert C, et al. Allergic rhinitis. Nat Rev Dis Primers. 2020;6(1):95. doi:10.1038/s41572-020-00227-0
1. Vandenplas O, Vinnikov D, Blanc PD, et al. Impact of rhinitis on work productivity: a systematic review. J Allergy Clin Immunol Pract. 2018;6(4):1274‐1286.e9.
1. Bhattacharyya N. Incremental healthcare utilization and expenditures for allergic rhinitis in the United States. Laryngoscope. 2011;121(9):1830‐1833.
1. de la Hoz Caballer B, Rodríguez M, Fraj J, Cerecedo I, Antolín‐Amérigo D, Colás C. Allergic rhinitis and its impact on work productivity in primary care practice and a comparison with other common diseases: the Cross‐sectional study to evAluate work Productivity in allergic Rhinitis compared with other common dIseases (CAPRI) study. Am J Rhinol Allergy. 2012;26(5):390‐394. doi:10.2500/ajra.2012.26.3799

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Patients' values and preferences for health states in allergic rhinitis-An artificial intelligence supported systematic review

Affiliations

Patients' values and preferences for health states in allergic rhinitis-An artificial intelligence supported systematic review

Authors

Affiliations

Abstract

References

REFERENCES

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Research Materials