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. 2024 Mar 28;187(7):1569-1573.
doi: 10.1016/j.cell.2024.02.043.

p53: A tale of complexity and context

Moshe Oren  1 , Carol Prives  2
Affiliations

p53: A tale of complexity and context

Moshe Oren et al. Cell. .

Abstract

The story of p53 is illuminating. Despite widespread attention, the tumor-suppressive functions of wild-type p53 or the oncogenic activities of its cancer-associated mutants are still not fully understood, and our discoveries have not yet led to major therapeutic breakthroughs. There is still much to learn about this fascinating protein.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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