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. 2024 Jun;132(6):1327-1329.
doi: 10.1016/j.bja.2024.02.026. Epub 2024 Mar 28.

Investigation of total 25-hydroxy vitamin D concentrations and postoperative delirium after major cardiac surgery

Jamie Sparling  1 , Laura Ketigian  2 , Jason Z Qu  1 , Ariel Mueller  1 , Isabella Turco  1 , Katia Colon  1 , Katherine Adelsberger  1 , Miriam Trigo  1 , Talia Colecchi  1 , Kwame Wiredu  1 , Oluwaseun Akeju  1 , Tina B McKay  3
Affiliations

Investigation of total 25-hydroxy vitamin D concentrations and postoperative delirium after major cardiac surgery

Jamie Sparling et al. Br J Anaesth. 2024 Jun.
No abstract available

Keywords: 1,25-dihydroxyvitamin D; Alzheimer's disease and related dementias; cardiopulmonary bypass; cognitive dysfunction; hypovitaminosis D; postoperative complications.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Fig 1
Fig 1
Preoperative total 25-OH vitamin D serum concentrations in the MINDDS cohort during the study period (March 2017–July 2021). (a) Vitamin D concentrations based on season of the year of sample collection. Data represented as median with 95% confidence intervals (n=390). (b) Vitamin D concentrations based on delirium status on postoperative day one through three (no delirium n=294 and delirium n=39). Data represented as median with boxes denoting the 25th and 75th percentiles (inter-quartile range) and whiskers extending to the minimum and maximum values for each group. (c) Distribution of patients based on delirium and vitamin D status, defined as: sufficient (≥30 ng ml−1), insufficient (21–29 ng ml−1), or deficient (≤20 ng ml−1). The percentage of subjects in each vitamin D class (sufficient, insufficient, deficient) per group (no delirium or delirium) is shown.
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