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Case Reports
. 2024 Feb 29;16(2):e55208.
doi: 10.7759/cureus.55208. eCollection 2024 Feb.

Exploring the Efficacy of Ketamine as an Anesthetic and Antidepressant in Postpartum Depression: A Case Study Analysis

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Case Reports

Exploring the Efficacy of Ketamine as an Anesthetic and Antidepressant in Postpartum Depression: A Case Study Analysis

Clara Benjamin et al. Cureus. .

Abstract

Postpartum depression is a common mental health disorder that affects women within six months after giving birth. It is characterized by sadness, anxiety, and extreme fatigue, which can significantly impact a woman's daily functioning and ability to care for her newborn. While traditional treatments for postpartum depression include therapy and medication, recent studies have shown promising results using ketamine. We present a case of a woman with a history of depression who delivered four children by cesarean section with debilitating postpartum depression in two births and no symptoms of depression in the births where she received ketamine during delivery.

Keywords: anesthesia; anti-depressants; ketamine; maternal mental health; postnatal depression; postpartum depression; pregnancy.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Risk factors for post-partum depression
Image Credit: Valerie McAllister (co-author)

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References

    1. Diagnostic and statistical manual of mental disorders: DSM-5. Vol. 5. Washington, DC: American Psychiatric Association; 2013. Diagnostic and statistical manual of mental disorders: DSM-5; p. 5.
    1. The role of reproductive hormones in postpartum depression. Schiller CE, Meltzer-Brody S, Rubinow DR. CNS Spectr. 2015;20:48–59. - PMC - PubMed
    1. Perinatal depression: a systematic review of prevalence and incidence. Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T. Obstet Gynecol. 2005;106:1071–1083. - PubMed
    1. Prevalence and risk factors of postpartum depression in women: a systematic review and meta-analysis. Liu X, Wang S, Wang G. https://doi.org/10.1111/jocn.16121. J Clin Nurs. 2022;31:2665–2677. - PubMed
    1. Consequences of maternal postpartum depression: a systematic review of maternal and infant outcomes. Slomian J, Honvo G, Emonts P, Reginster JY, Bruyère O. Womens Health (Lond) 2019;15:1745506519844044. - PMC - PubMed

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