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. 2024 Feb 27;14(1):28-34.
doi: 10.4103/jispcd.jispcd_67_23. eCollection 2024 Jan-Feb.

Little Ironweed and Java Tea in Herbal Toothpaste Reduced Dentine Permeability: An In Vitro Study

La-Ongthong Vajrabhaya  1 , Suwanna Korsuwannawong  2 , Cholthacha Harnirattisai  3 , Chayada Teanchai  2 , Weena Salee  2
Affiliations

Little Ironweed and Java Tea in Herbal Toothpaste Reduced Dentine Permeability: An In Vitro Study

La-Ongthong Vajrabhaya et al. J Int Soc Prev Community Dent. .

Abstract

Aim: To determine the effect of an herbal toothpaste containing Little Ironweed and Java Tea, on reducing dentine permeability in vitro.

Materials and methods: Dentine discs from human mandibular third molars were divided into three groups and brushed with herbal toothpaste, nonherbal toothpaste, or deionized water. Each group was immersed in artificial saliva (AS) or 6% citric acid. The permeability of each dentine disc was evaluated before and after saliva or acid challenge using a fluid filtration system. The morphology of dentine discs after treatment was observed using scanning electron microscopy (SEM). The mean permeabilities were statistically analyzed using analysis of variance and Tukey's test.

Results: The nonherbal and herbal toothpaste groups demonstrated reduced dentine permeability. AS immersion decreased dentine permeability in both toothpaste groups with values lower than the control group. Dentine permeability values increased after acid immersion in the toothpaste groups and were similar to each other. SEM revealed small granular crystal-like and round particles on the dentine surface and opening of dentinal tubules of both toothpaste groups. More dentinal tubules were opened after brushing with deionized water.

Conclusions: The reduction of dentine permeability caused by the herbal toothpaste was similar to that of the nonherbal toothpaste after brushing and the simulated oral conditions. Both herbal plants have the possibility to alleviate clinical hypersensitivity by reducing dentine permeability. Little Ironweed and Java Tea in the toothpaste composition is a potential choice for treating hypersensitive dentine.

Keywords: Dentine permeability; herbal and nonherbal toothpastes; tubules occlusion.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Schematic representation of methodology. A-E: Dentine disc preparation, F-G: SEM evaluation before and after H3PO4 application, H: Three experimental groups, I: Dentine permeability measurement, J: SEM evaluation. AS = artificial saliva
Figure 2
Figure 2
(A) Dentine disk after smear layer creation. (B) After 37% phosphoric acid treatment. 2000×
Figure 3
Figure 3
(A–C) Scanning electron microscopy of the dentine surfaces after brushing. (D–F) After immersion in artificial saliva. (G–I) After acid challenge. 2000×
See this image and copyright information in PMC

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References

    1. Chen CY, Hasselgren G. Lack of fluid movement between dentin tubule and pulp tissue: An in vitro study. Dent Hypotheses. 2022;13:67–9.
    1. Abuzinadah SH, Alhaddad AJ. A randomized clinical trial of dentine hypersensitivity reduction over one month after a single topical application of comparable materials. Sci Rep. 2021;11:6793. - PMC - PubMed
    1. Rajguru SA, Padhye AM, Gupta HS. Effects of two desensitizing dentifrices on dentinal tubule occlusion with citric acid challenge: Confocal laser scanning microscopy study. Indian J Dent Res. 2017;28:450–6. - PubMed
    1. Freda NM, Veitz-Keenan A. Calcium sodium phosphosilicate had some benefit on dentine hypersensitivity. Evid Based Dent. 2016;17:12–3. - PubMed
    1. Misra TN, Singh RS, Upadhyay J, Srivastava R. Chemical constituents of Vernonia cinerea, Part I. Isolation and spectral studies of triterpenes. J Nat Prod. 1984;47:368–72.