Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Aug 30;76(2):2201-2216.
doi: 10.32604/cmc.2023.041191.

SNSVM: SqueezeNet-Guided SVM for Breast Cancer Diagnosis

Affiliations

SNSVM: SqueezeNet-Guided SVM for Breast Cancer Diagnosis

Jiaji Wang et al. Comput Mater Contin. .

Abstract

Breast cancer is a major public health concern that affects women worldwide. It is a leading cause of cancer-related deaths among women, and early detection is crucial for successful treatment. Unfortunately, breast cancer can often go undetected until it has reached advanced stages, making it more difficult to treat. Therefore, there is a pressing need for accurate and efficient diagnostic tools to detect breast cancer at an early stage. The proposed approach utilizes SqueezeNet with fire modules and complex bypass to extract informative features from mammography images. The extracted features are then utilized to train a support vector machine (SVM) for mammography image classification. The SqueezeNet-guided SVM model, known as SNSVM, achieved promising results, with an accuracy of 94.10% and a sensitivity of 94.30%. A 10-fold cross-validation was performed to ensure the robustness of the results, and the mean and standard deviation of various performance indicators were calculated across multiple runs. This model also outperforms state-of-the-art models in all performance indicators, indicating its superior performance. This demonstrates the effectiveness of the proposed approach for breast cancer diagnosis using mammography images. The superior performance of the proposed model across all indicators makes it a promising tool for early breast cancer diagnosis. This may have significant implications for reducing breast cancer mortality rates.

Keywords: SqueezeNet; breast cancer diagnosis; support vector machine.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors declare that they have no conflicts of interest to report regarding the present study.

Figures

Figure 1
Figure 1. Examples of abnormal breast types in the mini-MIAS dataset
Figure 2
Figure 2. Structure of fire module
Figure 3
Figure 3. Original SqueezeNet structure
Figure 4
Figure 4. SqueezeNet with complex bypass
Figure 5
Figure 5. Separation hyperplane of SVM
Figure 6
Figure 6. Illustration of 10-fold cross-validation
Figure 7
Figure 7. Results of MDA
Figure 8
Figure 8. Accuracy convergence plot with iteration number
Figure 9
Figure 9. ROC curve
Figure 10
Figure 10. Comparison of SNSVM with other models

Similar articles

Cited by

References

    1. Aldrich J, Ekpo P, Rupji M, Switchenko JM, Torres MA, et al. Racial disparities in clinical outcomes on investigator-initiated breast cancer clinical trials at an urban medical center. Clinical Breast Cancer. 2023;23(1):38–44. - PubMed
    1. Dan WC, Guo XY, Zhang GZ, Wang SL, Deng M, et al. Integrative analyses of radiation-related genes and biomarkers associated with breast cancer. European Review for Medical and Pharmacological Sciences. 2023;27(1):256–274. - PubMed
    1. Roberts E, Howell S, Evans DG. Polygenic risk scores and breast cancer risk prediction. Breast. 2023;67(7):71–77. - PMC - PubMed
    1. Zatecky J, Kubala O, Jelinek P, Lerch M, Ihnat P, et al. Magnetic marker localisation in breast cancer surgery. Archives of Medical Science. 2023;19(1):122–127. - PMC - PubMed
    1. Sansone M, Fusco R, Grassi F, Gatta G, Belfiore MP, et al. Machine learning approaches with textural features to calculate breast density on mammography. Current Oncology. 2023;30(1):839–853. - PMC - PubMed

LinkOut - more resources