Intrinsic projections within visual cortex: evidence for orientation-specific local connections

Abstract

The functional organization of intrinsic connections within area 18 of cat visual cortex was studied using combined electrophysiological and anatomical techniques. Physiological recordings were first used to map the distribution of orientation preference, ocular dominance, and receptive-field location relative to the cortical surface. Next, localized injections of lectin-conjugated horseradish peroxidase were made into physiologically identified regions within area 18. We found that (i) the local cortical interconnections are made preferentially between cell populations with orthogonal preferred orientations and are independent of the ocular dominance of the cortical cells, (ii) the map of visual space in the cortex is anisotropic with the magnification factor for vertical at least twice that for horizontal visual space, and (iii) the pattern of cortical projections compensates for the functional asymmetry so that a population of interconnected cells represents a roughly circular region of visual space.