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. 2024 Jun 1;81(6):631-632.
doi: 10.1001/jamapsychiatry.2024.0299.

Heritability of Clinically Diagnosed Obsessive-Compulsive Disorder Among Twins

David Mataix-Cols  1 , Lorena Fernández de la Cruz  1 , Jan C Beucke  2 , Elles De Schipper  1 , Ralf Kuja-Halkola  3 , Paul Lichtenstein  3 , Josep Pol-Fuster  1
Affiliations

Heritability of Clinically Diagnosed Obsessive-Compulsive Disorder Among Twins

David Mataix-Cols et al. JAMA Psychiatry. .
No abstract available

Plain language summary

This cohort study estimates the heritability of clinically diagnosed obsessive-compulsive disorder in a sample of twins.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Mataix-Cols reported receiving personal fees from UpToDate, Inc outside the submitted work. Dr Fernández de la Cruz reported receiving grants from Åke Wiberg’s Foundation during the conduct of the study and receiving grants from the Heart and Lung Foundation (Hjärt-Lungfonden), the Swedish Research Council (Vetenskapsrådet), Folksam's Research Foundation (Folksams Forskningsstiftelse), and Karolinska Institutet and personal fees from Elsevier, UpToDate, Inc, and Wolters Kluwer Health outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Tetrachoric Correlations for Clinically Diagnosed Obsessive-Compulsive Disorder in Monozygotic (MZ) and Dizygotic (DZ) Twins
The MZ correlations are based on 22 493 twin pairs (18 767 complete pairs and 3726 incomplete pairs). The DZ correlations are based on 28 653 same-sex twin pairs (23 084 complete pairs and 5569 incomplete pairs) and 23 589 opposite-sex twin pairs (15 808 complete pairs and 7781 incomplete pairs).
See this image and copyright information in PMC

References

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