Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Jun;63(6):e105-e110.
doi: 10.1111/ijd.17153. Epub 2024 Apr 3.

Review of the use of Janus kinase inhibitors in the treatment of scarring alopecia

Ambika Nohria #  1 , Deesha Desai #  1   2 , Jerry Shapiro  1 , Lindsey Bordone  3 , Kristen Lo Sicco  1
Affiliations
Review

Review of the use of Janus kinase inhibitors in the treatment of scarring alopecia

Ambika Nohria et al. Int J Dermatol. 2024 Jun.
No abstract available

Keywords: JAK inhibitor; Janus kinase inhibitor; central centrifugal cicatricial alopecia; cicatricial alopecia; dissecting cellulitis of the scalp; folliculitis decalvans; frontal fibrosing alopecia; lichen planopilaris; scarring alopecia.

PubMed Disclaimer

References

    1. Filbrandt R, Rufaut N, Jones L, Sinclair R. Primary cicatricial alopecia: diagnosis and treatment. CMAJ. 2013;185(18):1579–1585. https://doi.org/10.1503/cmaj.111570
    1. Triyangkulsri K, Suchonwanit P. Role of janus kinase inhibitors in the treatment of alopecia areata. Drug Des Devel Ther. 2018;12:2323–2335. https://doi.org/10.2147/DDDT.S172638
    1. Shao S, Tsoi LC, Sarkar MK, Xing X, Xue K, Uppala R, et al. IFN‐γ enhances cell‐mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus. Sci Transl Med. 2019;11(511):eaav7561. https://doi.org/10.1126/scitranslmed.aav7561
    1. Del Duca E, Ruano Ruiz J, Pavel AB, Sanyal RD, Song T, Gay‐Mimbrera J, et al. Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing. Br J Dermatol. 2020;183(6):1083–1093. https://doi.org/10.1111/bjd.19040
    1. National Library of Medicine. Dual JAK1/TYK2 inhibitor for cicatricial. 2023.

LinkOut - more resources