Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jan-Feb;69(1):38-43.
doi: 10.4103/ijd.ijd_144_23. Epub 2024 Feb 27.

Quality of Life in Psoriasis: A Cross-Sectional Study from North India

Affiliations

Quality of Life in Psoriasis: A Cross-Sectional Study from North India

Khushboo Arora et al. Indian J Dermatol. 2024 Jan-Feb.

Abstract

Background: Psoriasis is a chronic inflammatory papulo-squamous disease characterized by multiple remissions and relapses. This study aimed to assess the impact of psoriasis on the quality of life of patients.

Materials and methods: A hospital-based, cross-sectional study was conducted enrolling 198 adult patients of psoriasis. The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines for observational studies were followed. Clinical severity of psoriasis was measured using Psoriasis Area Severity Index (PASI), and quality of life was measured by EuroQoL 5D (EQ-5D-5L, EQ-VAS) and Psoriasis Quality-Of-Life-12 (PQOL-12) Questionniares.

Results: Of the 198 patients, 71.7% (n = 142/198) were males with a mean age of 41.65 ± 13.19 years. The mean PASI score was 12.46 ± 11.51, and the mean PQOL-12 score was 50.18 ± 23.36. Up to 22.7% (n = 45) cases had 'severe' and 6.1% (n = 12) cases has 'very severe' PQOL-12 scores. Statistically significant correlation (P < 0.05) was observed between PASI scores and almost all domains of EQ-5D-5L and PQOL-12.

Conclusion: Psoriasis affects most psycho-social domains of a patient's life. Coping with these QOL issues remains a challenge to the patients in everyday life. The goal of management of psoriasis therefore must include measures to improve quality of life along with long-lasting remittance of physical symptoms.

Keywords: Pasi; QOL; psoriasis; quality of life.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Similar articles

References

    1. Mahajan R, Handa S. Pathophysiology of psoriasis. Indian J Dermatol Venereol Leprol. 2013;79((Suppl 7)):S1–9. - PubMed
    1. Sarkar R, Chugh S, Bansal S. General measures and quality of life issues in psoriasis. Indian Dermatol Online J. 2016;7:481–8. - PMC - PubMed
    1. Al-Mazeedi K, El-Shazly M, Al-Ajmi HS. Impact of psoriasis on quality of life in Kuwait. Int J Dermatol. 2006;45:418–24. - PubMed
    1. Finlay AY, Kelly SE. Psoriasis--an index of disability. Clin Exp Dermatol. 1987;12:8–11. - PubMed
    1. Jacobson CC, Kimball AB. Rethinking the psoriasis area and severity index: The impact of area should be increased. Br J Dermatol. 2004;151:381–7. - PubMed