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. 2024 Apr 30;30(2):208-219.
doi: 10.5056/jnm23090.

Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study

Kumi Nakaya  1   2 , Naoki Nakaya  1   2 , Mana Kogure  1   2 , Rieko Hatanaka  1   2 , Ippei Chiba  1   2 , Ikumi Kanno  1   2 , Satoshi Nagaie  1   2 , Tomohiro Nakamura  1   2   3 , Motoyori Kanazawa  2 , Soichi Ogishima  1   2 , Nobuo Fuse  1   2 , Shin Fukudo  2 , Atsushi Hozawa  1   2
Affiliations

Factors Associated With the Prevalence of Irritable Bowel Syndrome: The Miyagi Part of the Tohoku Medical Megabank Project Community-based Cohort Study

Kumi Nakaya et al. J Neurogastroenterol Motil. .

Abstract

Background/aims: The objective of this research is to examine factors related to irritable bowel syndrome (IBS) prevalence in a large population-based study.

Methods: A cross-sectional study was conducted with participants in the Miyagi part of the Tohoku Medical Megabank Project Community-Based cohort study who completed the Rome II Modular Questionnaire. Multivariate odds ratios (ORs) for the presence of IBS and 95% confidence intervals (95% CIs) for the reference group were calculated for each factor. Additionally, a stratified analysis was performed by sex and age group (20-49 years, 50-64 years, and ≥ 65 years).

Results: Among 16 252 participants, 3025 (18.6%) had IBS, comprising 750 men (15.5%) and 2275 women (19.9%). Multivariate ORs for the presence of IBS decreased significantly with each year of age (OR, 0.98; 95% CI, 0.98-0.99). Moreover, compared with the reference group, ORs for the presence of IBS were significantly higher in individuals whose home was partially damaged by the Great East Japan Earthquake, those with < 16 years of education, those who spent less time walking, those with high perceived stress (1.77, 1.57-2.01), those with high psychological distress (1.58, 1.36-1.82), and those with high symptoms of depression (1.76, 1.60-1.94). In stratified analyses, a significant relationship was found between psychological factors and IBS prevalence in all sex and age groups.

Conclusions: This large cross-sectional population-based cohort study identified several factors associated with IBS prevalence. Psychological factors were significantly associated with IBS prevalence across all age groups and sexes.

Keywords: Cross-sectional studies; Irritable bowel syndrome; Prevalence; Tohoku Medical Megabank Project Community-based cohort study.

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Conflict of interest statement

Conflicts of interest: None.

Figures

Figure 1
Figure 1
Study flowchart.
Figure 2
Figure 2
Age-sex distribution of participants (N = 16 252).
Figure 3
Figure 3
Prevalence of irritable bowel syndrome by year and degree of damage to the home due to the disaster.
See this image and copyright information in PMC

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