Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Mar 21:11:1332080.
doi: 10.3389/fmed.2024.1332080. eCollection 2024.

High-intensity focused ultrasound for endometrial ablation in adenomyosis: a clinical study

Siyun Wu #  1 , Jun Liu #  1 , Xiaoshan Liu  1 , Yanhua Han  1
Affiliations

High-intensity focused ultrasound for endometrial ablation in adenomyosis: a clinical study

Siyun Wu et al. Front Med (Lausanne). .

Abstract

Objective: The present study aimed to investigate the clinical efficacy of endometrial ablation with high-intensity focused ultrasound (HIFU) for symptom relief in women with adenomyosis.

Methods: Between July 2014 and July 2020, 167 patients with adenomyosis treated at the Zhongshan City People's Hospital were enrolled in this study. Patients were divided into two groups according to patient aspirations: the control group, including patients who only underwent ablation of adenomyosis lesions (group A) and the treatment group, including patients who underwent removal of adenomyosis lesions and endometrial ablation (group B).

Results: The reduced dysmenorrhea scores (visual analog scale) and menstrual volume scores (pictorial blood assessment chart) were measured before and after treatment. The scores were obtained by subtracting the postoperative scores from the preoperative scores and were compared to determine whether the symptoms had alleviated. Compared with the menstrual volume of group A, that in group B showed significant improvements. The average relief rates of dysmenorrhea in the two groups also showed significant improvement. However, the scores in group B showed a more significant improvement than those in group A.

Conclusion: Therefore, our findings suggest that endometrial ablation using HIFU may be superior to conventional therapy with regard to alleviating the symptoms of increased menstruation in women with adenomyosis.

Keywords: adenomyosis; dysmenorrhea; endometrium; high-intensity focused ultrasound; magnetic resonance imaging.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The measurement of the volume of adenomyotic lesions (volume = 0.5233 × a × b × c).
Figure 2
Figure 2
The measurement of the volume of the destroyed lesions (volume = 0.5233 × a × b × c).
Figure 3
Figure 3
The measurement of the area of endometrium (area = 0.5 × a × b × 2).
Figure 4
Figure 4
The measurement of the area of frustrated endometrium (area = 0.5 × a × b + 0.5 × c × d).
Figure 5
Figure 5
Reduction of VAS in patients after HIFU treatment. VAS, visual analog scale; HIFU, high-intensity focused ultrasound.
Figure 6
Figure 6
Reduction of menstrual volumes in patients after HIFU treatment. HIFU, high-intensity focused ultrasound.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Sudderuddin S, Helbren E, Telesca M, Williamson R, Rockall A. MRI appearances of benign uterine disease. Clin Radiol. (2014) 69:1095–104. doi: 10.1016/j.crad.2014.05.108 - DOI - PubMed
    1. Shrestha A, Shrestha R, Sedhai LB, Pandit U. Adenomyosis at hysterectomy: prevalence, patient characteristics, clinical profile and histopatholgical findings. Kathmandu Univ Med J. (2012) 10:53–6. doi: 10.3126/kumj.v10i1.6915, PMID: - DOI - PubMed
    1. Tsai MC, Chang LT, Tam KW. Comparison of high-intensity focused ultrasound and conventional surgery for patients with uterine myomas: a systematic review and meta-analysis. J Minim Invasive Gynecol. (2021) 28:1712–24. doi: 10.1016/j.jmig.2021.06.002, PMID: - DOI - PubMed
    1. Zhang L, Rao F, Setzen R. High intensity focused ultrasound for the treatment of adenomyosis: selection criteria, efficacy, safety and fertility. Acta Obstet Gynecol Scand. (2017) 96:707–14. doi: 10.1111/aogs.13159, PMID: - DOI - PubMed
    1. Kishi Y, Suginami H, Kuramori R, Yabuta M, Suginami R, Taniguchi F. Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification. Am J Obstet Gynecol. (2012) 207:114.e1-7. doi: 10.1016/j.ajog.2012.06.027, PMID: - DOI - PubMed

LinkOut - more resources