Major depression mistaken as frontotemporal dementia due to PET scan

doi:10.1177/20542704241241113

Case Reports

. 2024 Apr 2;15(4):20542704241241113.

doi: 10.1177/20542704241241113. eCollection 2024 Apr.

Major depression mistaken as frontotemporal dementia due to PET scan

Martin Bystad¹, Ole Grønli^{1

2}, Rolf Wynn^{2

3}

Affiliations

¹ Division of Substance Use and Mental Health, University Hospital of North Norway, Tromsø, Norway.
² Department of Clinical Medicine, UiT The Arctic University of Tromsø, Tromsø, Norway.
³ Department of Education, ICT and Learning, Østfold University College, Halden, Norway.

PMID: 38576770
PMCID: PMC10989049
DOI: 10.1177/20542704241241113

Case Reports

Major depression mistaken as frontotemporal dementia due to PET scan

Martin Bystad et al. JRSM Open. 2024.

. 2024 Apr 2;15(4):20542704241241113.

doi: 10.1177/20542704241241113. eCollection 2024 Apr.

Authors

Martin Bystad¹, Ole Grønli^{1

2}, Rolf Wynn^{2

3}

Affiliations

¹ Division of Substance Use and Mental Health, University Hospital of North Norway, Tromsø, Norway.
² Department of Clinical Medicine, UiT The Arctic University of Tromsø, Tromsø, Norway.
³ Department of Education, ICT and Learning, Østfold University College, Halden, Norway.

PMID: 38576770
PMCID: PMC10989049
DOI: 10.1177/20542704241241113

Abstract

Clinicians should be aware that the hypometabolism associated with depression can mimic frontotemporal dementia on PET.

Keywords: Frontotemporal dementia; PET; depression; neuroimage; neuropsychology.

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References

1. Olney NT, Spina S, Miller BL. Frontotemporal dementia. Neurol Clin 2017;35(2):339–374. - PMC - PubMed
1. Leroy M, Bertoux M, Skrobala E, Mode E, Adnet-Bonte C, Le Ber I, et al.. Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network. Alzheimers Res Ther 2021;13(1):19. - PMC - PubMed
1. Rosso SM, Donker Kaat L, Baks T, Joosse M, de Koning I, Pijnenburg Y, et al.. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 2003;126(Pt 9):2016–2022. - PubMed
1. Zhao M, Lv X, Tuerxun M, He J, Luo B, Chen W, et al.. Clinical pathway for Alzheimer’s disease in China (CPAD) investigators. Delayed help seeking behavior in dementia care: preliminary findings from the Clinical Pathway for Alzheimer's Disease in China (CPAD) study. Int Psychogeriatr 2016;28(2):211–219. - PubMed
1. Pose M, Cetkovich M, Gleichgerrcht E, Ibáñez A, Torralva T, Manes F. The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry 2013;25(2):159–167. - PubMed

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[1] Olney NT, Spina S, Miller BL. Frontotemporal dementia. Neurol Clin 2017;35(2):339–374. - PMC - PubMed

[2] Olney NT, Spina S, Miller BL. Frontotemporal dementia. Neurol Clin 2017;35(2):339–374. - PMC - PubMed

[3] Leroy M, Bertoux M, Skrobala E, Mode E, Adnet-Bonte C, Le Ber I, et al.. Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network. Alzheimers Res Ther 2021;13(1):19. - PMC - PubMed

[4] Leroy M, Bertoux M, Skrobala E, Mode E, Adnet-Bonte C, Le Ber I, et al.. Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network. Alzheimers Res Ther 2021;13(1):19. - PMC - PubMed

[5] Rosso SM, Donker Kaat L, Baks T, Joosse M, de Koning I, Pijnenburg Y, et al.. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 2003;126(Pt 9):2016–2022. - PubMed

[6] Rosso SM, Donker Kaat L, Baks T, Joosse M, de Koning I, Pijnenburg Y, et al.. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 2003;126(Pt 9):2016–2022. - PubMed

[7] Zhao M, Lv X, Tuerxun M, He J, Luo B, Chen W, et al.. Clinical pathway for Alzheimer’s disease in China (CPAD) investigators. Delayed help seeking behavior in dementia care: preliminary findings from the Clinical Pathway for Alzheimer's Disease in China (CPAD) study. Int Psychogeriatr 2016;28(2):211–219. - PubMed

[8] Zhao M, Lv X, Tuerxun M, He J, Luo B, Chen W, et al.. Clinical pathway for Alzheimer’s disease in China (CPAD) investigators. Delayed help seeking behavior in dementia care: preliminary findings from the Clinical Pathway for Alzheimer's Disease in China (CPAD) study. Int Psychogeriatr 2016;28(2):211–219. - PubMed

[9] Pose M, Cetkovich M, Gleichgerrcht E, Ibáñez A, Torralva T, Manes F. The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry 2013;25(2):159–167. - PubMed

[10] Pose M, Cetkovich M, Gleichgerrcht E, Ibáñez A, Torralva T, Manes F. The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry 2013;25(2):159–167. - PubMed

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Major depression mistaken as frontotemporal dementia due to PET scan

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Major depression mistaken as frontotemporal dementia due to PET scan

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