Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Mar 16;12(8):1530-1535.
doi: 10.12998/wjcc.v12.i8.1530.

Analysis and monitoring of drug therapy in a patient with peptic ulcer complicated by infection: A case report

Affiliations
Case Reports

Analysis and monitoring of drug therapy in a patient with peptic ulcer complicated by infection: A case report

Yan-Ping Gou et al. World J Clin Cases. .

Abstract

Background: The role of primary-level medical pharmacists in medical institutions in China is limited; therefore, it is necessary to explore the role of pharmacists in the process of drug treatment.

Case summary: A Chinese pharmacist participated in the complete treatment of a patient with a duodenal ulcer. The rationale for drug treatment was evaluated, and adjustments were made to the antacid and anti-infective regimen, as well as the dose and frequency of administration. Body temperature, routine blood examination, and adverse drug reactions were strictly monitored. During treatment, the pharmacist recommended anti-infective therapy with ampicillin-sulbactam, which effectively controlled the infection. Additionally, the pharmacist suggested changing famotidine to lansoprazole for acid suppression and gastroprotective treatment, combined with Chinese patent medicine such as Kangfuxin Liquid. This is the first case report of a pharmacist in primary-level medical institutions adjusting drug use for patients with duodenal ulcer and pulmonary infection.

Conclusion: A pharmacist participated in the treatment process, provided individualized medication adjustment, and achieved good clinical results.

Keywords: Ampicillin–sulbactam; Case report; Chinese pharmacist; Famotidine; Kangfuxin Liquid; Lansoprazole.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Pharmacist intervention and follow-up results.

References

    1. Jacob TV, Doshi GM. New promising routes in peptic ulcers: Toll-like receptors and semaphorins. Endocr Metab Immune Disord Drug Targets. 2023 - PubMed
    1. Duggan JM, Duggan AE. The possible causes of the pandemic of peptic ulcer in the late 19th and early 20th century. Med J Aust. 2006;185:667–669. - PubMed
    1. Alsahafi M, Mosli M, Alkhowaiter S, Donnellan F. Decision-Utility Analysis of Empiric Treatment Versus Test and Treat Strategies for Helicobacter pylori in Patients With Duodenal Ulcer. Value Health Reg Issues. 2024;39:1–5. - PubMed
    1. Talebi Bezmin Abadi A. Helicobacter pylori treatment: New perspectives using current experience. J Glob Antimicrob Resist. 2017;8:123–130. - PubMed
    1. Fong ZV, McMillan MT, Marchegiani G, Sahora K, Malleo G, De Pastena M, Loehrer AP, Lee GC, Ferrone CR, Chang DC, Hutter MM, Drebin JA, Bassi C, Lillemoe KD, Vollmer CM, Fernández-Del Castillo C. Discordance Between Perioperative Antibiotic Prophylaxis and Wound Infection Cultures in Patients Undergoing Pancreaticoduodenectomy. JAMA Surg. 2016;151:432–439. - PubMed

Publication types