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Case Reports
. 2024 Mar 6;86(4):2194-2199.
doi: 10.1097/MS9.0000000000001923. eCollection 2024 Apr.

Renal vein thrombosis in a patient secondary to high-grade rhabdoid renal cell carcinoma: a case report and review of literature

Manish Kc  1 , Himal Bikram Bhattarai  2 , Pratik Subedi  3 , Ashutosh Kashyap  4 , Manish Wadhwa  1 , Dania Kaur  1 , Sabina Koirala  5 , Swotantra Gautam  6
Affiliations
Case Reports

Renal vein thrombosis in a patient secondary to high-grade rhabdoid renal cell carcinoma: a case report and review of literature

Manish Kc et al. Ann Med Surg (Lond). .

Abstract

Introduction: Renal cell carcinoma, a common kidney tumour which is often incidentally discovered on imaging, can manifest with atypical symptoms. Renal cell carcinoma with rhabdoid features is a rare occurrence and even rarer in case of adults. Renal cell carcinoma has the tendency to form thrombus that can migrate to renal vein, inferior vena cava and even right atrium.

Case presentation: The authors report a case of an 81-year-old male with rhabdoid renal cell carcinoma presenting with persistent cough for 6-7 months. with tumour thrombus extending into the renal vein and hepatic inferior vena cava. The patient was found feeble for the surgery and hence was treated on anticancer drugs pembrolizumab and axitinib.

Conclusion: Renal cell carcinoma has the tendency to form tumour thrombus in renal vein and inferior vena cava. Prognosis without surgical intervention in these conditions is very poor.

Keywords: Case report; renal cell carcinoma; rhabdoid; thrombosis.

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Conflict of interest statement

None.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

Figures

Figure 1
Figure 1
Computed tomography head suggestive of hyperacute parenchymal lobar haemorrhage showing haematocrit effect and measuring 8 cm3 in right frontal lobe with minimal Perifocal OEdema.
Figure 2
Figure 2
Computed tomography head suggestive of two large epicentres of acute parenchymal haemorrhage measuring 41 cm3 in right frontal lobe and 32 cm3 posterior to it in right temporo parietal lobe with perifocal hypoattenuation.
Figure 3
Figure 3
Computed tomography head post right fronto parieto temporal decompressive craniectomy and evacuation of right fronto parietal haemorrhage with features suggestive of mild dural Bulge, minimal residual haemorrhage anteriorly, perifocal oedema, midline shift measuring 5 mm with minimal surrounding oedema.
Figure 4
Figure 4
Computed tomography head of the patient before getting discharged with features suggestive of decompressive craniectomy changes in right fronto parietal area, minimal residual haemorrhage in right frontal lobe with trace oedema without any midline shift.
See this image and copyright information in PMC

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