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. 2024 Feb 16;86(4):1867-1872.
doi: 10.1097/MS9.0000000000001840. eCollection 2024 Apr.

Cholangioscopy with Spyglass DS using percutaneous transhepatic cholangiography access: a retrospective cohort study

Trygve Ulvund Solstad  1 , Morten Thorsteinsson  1 , Nicolai Schultz  1 , Peter Nørgaard Larsen  1 , Mikkel Taudorf  2   3 , Michael Achiam  1   3
Affiliations

Cholangioscopy with Spyglass DS using percutaneous transhepatic cholangiography access: a retrospective cohort study

Trygve Ulvund Solstad et al. Ann Med Surg (Lond). .

Abstract

Background: Conventional peroral methods to visualize biliary strictures are not feasible in some patients with altered anatomy or biliary obstruction, and percutaneous transhepatic cholangioscopy can be used as an alternative procedure. This study aimed to retrospectively review the use of percutaneous transhepatic cholangiography using the SpyGlass DS technology (S-PTCS) during a 5-year period at a Danish tertiary referral centre.

Materials and methods: All patients who underwent S-PTCS at a single Danish tertiary referral centre between 2016 and 2021 were retrospectively analyzed. The visual, technical, and overall success rates of S-PTCS were analyzed, as well as the complication rate. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of S-PTCS were calculated.

Results: Twenty-two patients were included in the study. Visual, technical, and overall success of S-PTCS was achieved in 17/22, 22/22, and 21/22 patients, respectively. S-PTCS yielded a sensitivity of 83.3%, a specificity of 100%, a PPV of 100%, a NPV of 94.1%, and an accuracy of 95.4%. Complications occurred in 1/22 patients.

Conclusion: S-PTCS is a safe modality, with high success rates, high predictive values, and a low rate of complications. This study suggests that S-PTCS is an alternative to conventional methods in patients with indeterminate biliary strictures where conventional methods were unfeasible.

Keywords: Indeterminate biliary strictures; SpyGlass; percutaneous SpyGlass DS; percutaneous cholangioscopy.

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Conflict of interest statement

The authors report no proprietary or commercial interest in any product mentioned or concept discussed in this article. This research did not receive any specific grants from funding agencies in the public, commercial, or not-for-profit sectors. This is an original article, not based on previous communication with a society or meeting.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

Figures

Picture 1
Picture 1
Percutaneous transhepatic cholangioscopy with SpyGlass DS technology.
Picture 2
Picture 2
Normal intraductal tissue and guidewire visualized by SpyGlass DS.
Picture 3
Picture 3
Suspect intraductal tissue visualized by SpyGlass DS technology.
Picture 4
Picture 4
Intraductal tissue and SpyBite biopsy forceps visualized by SpyGlass DS technology.
See this image and copyright information in PMC

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