A potential difference across mouse ovarian follicle

Abstract

A small potential difference (antrum positive) has been measured with fine-tipped glass microelectrodes across the epithelial cell layers of the mouse ovarian follicle wall. As ovulation approached the potential in the antrum became more positive compared to the outside. Metabolic inhibitors and locally active hormones also altered the potential difference. The ionic basis and the significance of the potential difference are unknown.