Clinical efficacy of precision liver resection for primary liver cancer

Abstract

Aim: Precision liver resection is considered the gold standard in liver surgery. Therefore, optimizing the resection of lesions and minimizing unnecessary time of liver ischemia and hypoxia have become focal points.

Methods: A total of 96 patients with primary liver cancer admitted to Cangzhou People's Hospital from January 2017 and December 2019 were included in this retrospective study, and divided into two groups according to the different surgical treatment, with 50 cases in the control group (conventional hepatic resection) and 46 cases in the observation group (precision liver resection). The surgical indicators, liver function, alpha-fetoprotein (AFP), complications, and three-year follow-up results were analyzed in the two groups.

Results: The operation time, intraoperative bleeding, hospital stay, and time of anal venting in the observation group were shorter than those in the control group (P<0.05). One week after surgery, AST, TBiL, ALT, and γ-GT levels decreased in both groups, with more significant decreases in the observation group than those in the control group (P<0.05). PCT and hs-CRP levels in the observation group were significantly lower than those in the control group (P<0.05) observation. The incidences of pleural effusion, bile leak, abdominal infection, pulmonary infection, as well as the total complication rates in the observation group were lower in the observation group than those in the control group (P<0.05). The follow-up data revealed that the observation group exhibited a lower recurrence rate observationand higher survival rate than the control group within 3 years, but these differences were not significant (P>0.05).

Conclusion: Precision liver resection can effectively treat primary liver cancer, reduce the incidence of complications, and promote patient recovery after surgery.

Keywords: Precision liver resection; clinical curative effect; primary liver cancer.

Figure 1

Kaplan Meier survival curves.

Figure 2

Comparison of inflammatory indicators between the two groups. A: hs-CRP; B: PCT; C: IgG. Note: PCT: procalcitonin; IgG: Immunoglobin G; hs-CRP: high-sensitivity C-reactive protein. *P<0.05 as compared with control group, **P<0.01 as compared with control group, ***P<0.001 as compared with control group.