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Clinical Trial
. 1979 May-Jun;6(3):345-50.

Oxaprozin: a once-daily treatment regimen in rheumatoid arthritis

  • PMID: 385873
Clinical Trial

Oxaprozin: a once-daily treatment regimen in rheumatoid arthritis

W J Reynolds et al. J Rheumatol. 1979 May-Jun.

Abstract

The development of oxaprozin provided an opportunity to evaluate the control of inflammation in rheumatoid arthritis by a drug that can be administered once daily. A double-blind 12-week evaluation suggested comparable efficacy between 1,200 mg oxaprozin given as a single daily dose and 3,900 mg ASA given in 4 equally divided doses. A lower incidence of side effects was noted in the oxaprozin group. An open 6-month study substantiated the efficacy and safety of oxaprozin.

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