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. 2024 May 7;331(17):1496-1499.
doi: 10.1001/jama.2024.3917.

Cardiac Function Before Sepsis and Clinical Outcomes

Affiliations

Cardiac Function Before Sepsis and Clinical Outcomes

Stuthi Iyer et al. JAMA. .
No abstract available

Plain language summary

This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Seymour and Mr Kennedy reported receiving a grant from the National Institutes of Health (NIH)/National Institute of General Medical Sciences during the conduct of this study and outside the submitted work. Dr Seymour also reported receiving personal fees from Octapharma, Inotrem, and Beckman Coulter outside the submitted work. No other disclosures were reported.

Figures

Figure.
Figure.. Mortality Stratified by Type of Preexisting Cardiac Dysfunction During 5 Years After Sepsis Hospitalization
Log-rank P < .001 for comparison across groups among whom TTE was performed. BV indicates biventricular; LV, left ventricular; RV, right ventricular; and TTE, transthoracic echocardiography.

References

    1. Rhee C, Dantes R, Epstein L, et al. ; CDC Prevention Epicenter Program . Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014. JAMA. 2017;318(13):1241-1249. doi:10.1001/jama.2017.13836 - DOI - PMC - PubMed
    1. Yealy DM, Kellum JA, Huang DT, et al. ; ProCESS Investigators . A randomized trial of protocol-based care for early septic shock. N Engl J Med. 2014;370(18):1683-1693. doi:10.1056/NEJMoa1401602 - DOI - PMC - PubMed
    1. Parker MM, Shelhamer JH, Bacharach SL, et al. . Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med. 1984;100(4):483-490. doi:10.7326/0003-4819-100-4-483 - DOI - PubMed
    1. Seymour CW, Liu VX, Iwashyna TJ, et al. . Assessment of clinical criteria for sepsis: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):762-774. doi:10.1001/jama.2016.0288 - DOI - PMC - PubMed

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