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Case Reports
. 2024 Mar 19:53:101370.
doi: 10.1016/j.gore.2024.101370. eCollection 2024 Jun.

Primary peritoneal clear cell carcinoma arising in the setting of abdominal wall Endometriosis: A case report and review of the literature

Cameron M Harris  1 , Miller P Singleton  2 , Theresa Samulski  3 , Leslie H Clark  4
Affiliations
Case Reports

Primary peritoneal clear cell carcinoma arising in the setting of abdominal wall Endometriosis: A case report and review of the literature

Cameron M Harris et al. Gynecol Oncol Rep. .

Abstract

•Primary peritoneal clear cell carcinoma can arise from endometriotic implants within the abdomen and pelvis.•Immunohistochemistry can be used to confirm primary disease site. Endometriotic origin can be inferred based on clinical history and intraoperative findings suggestive of endometriosis.•While no standardized treatment exists, consideration should be given to cytoreductive surgery with adjuvant chemotherapy. Adjuvant radiation can also be considered for local control.

Keywords: Clear cell carcinoma; Endometriosis; Primary peritoneal cancer.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
CT findings demonstrating a new right lower quadrant mass.
Fig. 2
Fig. 2
Histology and Immunohistochemistry. (A) Papillary pattern with rounded papillae with hyalinized cores and characteristic hobnailing. (B) Tubulocystic pattern with glandular structures in a hyalinized background. Cells demonstrate eosinophilic to clear cytoplasm with variable nuclear pleomorphism. (C) Tumor cells diffusely positive for CK7. (D) Tumor cells were diffusely positive for Napsin-A. (E) Tumor cells were negative for WT-1, ER. (F) Tumor cells were diffusely positive for PAX-8.
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