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Review
. 2024 Feb 20;13(5):1185.
doi: 10.3390/jcm13051185.

Update on Diagnosis and Treatment of Uveitic Glaucoma

Ioannis Halkiadakis  1 , Kalliroi Konstantopoulou  1 , Vasilios Tzimis  1 , Nikolaos Papadopoulos  1 , Klio Chatzistefanou  2 , Nikolaos N Markomichelakis  3
Affiliations
Review

Update on Diagnosis and Treatment of Uveitic Glaucoma

Ioannis Halkiadakis et al. J Clin Med. .

Abstract

Glaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias in the interpretation of optical coherence tomography measurements. For the successful treatment of UG, the control of intraocular inflammation specific to the cause or anti-inflammatory treatment, combined with IOP management, is mandatory. The early institution of specific treatment improves the prognosis of UG associated with CMV. The young age of UG patients along with increased failure rates of glaucoma surgery in this group of patients warrants a stepwise approach. Conservative and conjunctival sparing surgical approaches should be adopted. Minimally invasive surgical approaches were proved to be effective and are increasingly being used in the management of UG along with the traditionally used techniques of trabeculectomy or tubes. This review aims to summarize the progress that recently occurred in the diagnosis and treatment of UG.

Keywords: Ahmed valve; Baerveldt tube; CMV; inflammatory glaucoma; minimally invasive glaucoma surgrery; uveitic glaucoma.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
CMV anterior uveitis with characteristic large keratic precipates.
Figure 2
Figure 2
Angle-closure glaucoma with iris bombe.
Figure 3
Figure 3
Retinal nerve fiber layer thickness before (A) and during (B) inflammation.
See this image and copyright information in PMC

References

    1. Acharya N.R., Tham V.M., Esterberg E., Borkar D.S., Parker J.V., Vinoya A.C., Uchida A. Incidence and prevalence of uveitis: Results the Pacific ocular inflammation study. JAMA Ophthalmol. 2013;131:1405–1412. doi: 10.1001/jamaophthalmol.2013.4237. - DOI - PubMed
    1. Gritz D., Wong I.G. Incidence and prevalence of uveitis in northern California the Northern California epidemiology of uveitis study. Ophthalmology. 2004;111:491–500. doi: 10.1016/j.ophtha.2003.06.014. - DOI - PubMed
    1. Miettinen R. Incidence of uveitis in northern Finland. Acta Ophthalmol. 1997;55:252–260. doi: 10.1111/j.1755-3768.1977.tb01306.x. - DOI - PubMed
    1. Suhler E.B., Lloyd M.J., Choi D., Rosenbaum J.T., Austin D.F. Incidence and prevalence of uveitis in Veterans Affairs medical centers of the Pacific Northwest. Am. J. Ophthalmol. 2008;146:890. doi: 10.1016/j.ajo.2008.09.014. - DOI - PubMed
    1. Van Tran T., Auer C., Guex-Crosier Y., Pittet N., Herbort C.P. Epidemiological characteristics of uveitis in Switzerland. Int. Ophthalmol. 1994;18:293–298. doi: 10.1007/BF00917833. - DOI - PubMed

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