Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May 1;37(5):22-27.
doi: 10.1097/01.JAA.0000000000000001. Epub 2024 Apr 25.

Acute liver failure

Affiliations

Acute liver failure

James Beck et al. JAAPA. .

Abstract

Acute liver failure, commonly caused by acetaminophen overdose, is associated with numerous systemic complications including cerebral edema, hypotension, acute kidney injury, and infection. Management is primarily supportive, with an emphasis on excellent neurocritical care. Although some antidotes and targeted treatments exist, the only definitive treatment remains orthotopic liver transplant.

PubMed Disclaimer

Similar articles

References

    1. Shingina A, Mukhtar N, Wakim-Fleming J, et al. Acute liver failure guidelines. Am J Gastroenterol . 2023;118(7):1128–1153.
    1. O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet . 1993;342(8866):273–275.
    1. Bernuau J, Benhamou JP. Classifying acute liver failure. Lancet . 1993;342(8866):252–253.
    1. Bernal W, Wendon J. Acute liver failure. N Engl J Med . 2013;369(26):2525–2534.
    1. Stravitz RT, Lee WM. Acute liver failure. Lancet . 2019;394(10201):869–881.

MeSH terms

LinkOut - more resources