Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 1;97(2S Suppl 1):S24-S26.
doi: 10.1097/TA.0000000000004343. Epub 2024 Apr 10.

Should soldiers take oral tranexamic acid before going into battle?

Nicolas Cazes  1 , Simon-Pierre Corcostegui, Steven Lovi, Emeric Romary, Vincent Desrobert, Lionel Lidzborski, Clément Derkenne
Affiliations

Should soldiers take oral tranexamic acid before going into battle?

Nicolas Cazes et al. J Trauma Acute Care Surg. .

Abstract

Tranexamic acid is an inexpensive antifibrinolytic treatment that reduces morbidity and mortality in civilian and military trauma patients. It must be administered within 3 hours of the injury, and its efficacy is greater the earlier it is given. It is already used preventively in the civilian environment in a number of indications to reduce bleeding and bleeding-related mortality. We wondered about the potential benefits of preventive oral administration of tranexamic acid prior to an assault for military personnel with a potential risk of injury.

PubMed Disclaimer

References

    1. Epstein A, Lim R, Johannigman J, Fox CJ, Inaba K, Vercruysse GA, et al. Putting medical boots on the ground: lessons from the war in Ukraine and applications for future conflict with near-peer adversaries. J Am Coll Surg . 2023;237(2):364–373.
    1. Gayet-Ageron A, Prieto-Merino D, Ker K, Shakur H, Ageron FX, Roberts I, et al. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Lancet . 2018;391(10116):125–132.
    1. Stevens RA, Baker MS, Zubach OB, Samotowka M. Misuse of tourniquets in Ukraine may be costing more lives and limbs than they save. Mil Med . 2024;usad503.
    1. Tactical Combat Casualty Care (TCCC) Guidelines for Medical Personnel 15 December 2021. J Spec Oper Med . 2022;22(1):11–17.
    1. Kotwal RS, Montgomery HR, Kotwal BM, Champion HR, Butler FK Jr., Mabry RL, et al. Eliminating preventable death on the battlefield. Arch Surg . 2011;146(12):1350–1358.

MeSH terms

LinkOut - more resources