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Case Reports
. 2024 Jan 22;23(1):43-45.
doi: 10.1055/s-0044-1778710. eCollection 2024 Mar.

Unusual Metastatic Sites of Testis and Rectum in Prostate Cancer Detected by 68 Ga-PSMA-11 PET/CT Imaging at Initial Staging

Rahul V Parghane  1   2 , Sandip Basu  1   2
Affiliations
Case Reports

Unusual Metastatic Sites of Testis and Rectum in Prostate Cancer Detected by 68 Ga-PSMA-11 PET/CT Imaging at Initial Staging

Rahul V Parghane et al. World J Nucl Med. .

Abstract

Imaging plays a pivotal role in defining the extent of disease and deciding therapeutic strategies in recently diagnosed high-risk prostate cancer. Standard-of-care conventional imaging may often miss rare metastatic disease sites. We herein present a unique case of prostate cancer where 68 Ga-PSMA-11 positron emission tomography (PET)/computed tomography (CT) detected two unusual metastatic sites (testis and rectum) in a single patient at initial staging, resulting in an accurate determination of the extent of disease, more tailored multimodal treatment planning, and exploration of the theragnostic potential.

Keywords: 68 Ga-PSMA-11 PET/CT; metastatic disease to the testes and rectum; prostate cancer; prostate-specific membrane antigen; theranostics.

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Conflict of interest statement

Conflict of Interest None declared.

Figures

Fig. 1
Fig. 1
( A ) Maximum-intensity projection image of 68 Ga-PSMA-11 positron emission tomography (PET)/computed tomography (CT) scan showing extensive prostate-specific membrane antigen (PSMA) uptake in skeleton, abdominopelvic, and scrotal regions. ( B ) Transaxial image of 68 Ga-PSMA-11 PET/CT showing PSMA-avid (SUVmax-19) large-sized prostatic mass lesion ( green arrow ) and rectal lesion ( blue arrow ). Scrotal PSMA uptake (SUVmax-18) localized to the left testicular lesion ( yellow arrow ) with associated hydrocele shown in fused ( C ) sagittal and ( D ) transaxial PET/CT.
See this image and copyright information in PMC

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