Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Mar 9;13(1):89580.
doi: 10.5409/wjcp.v13.i1.89580.

Evolving strategies: Enhancements in managing eosinophilic esophagitis in pediatric patients

Affiliations
Review

Evolving strategies: Enhancements in managing eosinophilic esophagitis in pediatric patients

Ahmed Elghoudi et al. World J Clin Pediatr. .

Abstract

Eosinophilic esophagitis is a newly recognized disease first described about 50 years ago. The definition, diagnosis, and management have evolved with new published consensus guidelines and newly approved treatment available to pediatricians, enabling a better understanding of this disease and more targeted treatment for patients. We describe the definition, presentation, and diagnosis of eosinophilic esophagitis including management, challenges, and future directions in children. The definition, diagnosis, and management of eosinophilic esophagitis have evolved over the last 50 years. Consensus guidelines and newly approved biologic treatment have enabled pediatricians to better understand this disease and allow for more targeted treatment for patients. We describe the definition, presentation, diagnosis, management, and treatment in addition to the challenges and future directions of eosinophilic esophagitis management in children.

Keywords: Dysphagia; Eosinophilic esophagitis; Esophagitis; Food allergy; Gastroesophageal reflux disease.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Relationship between symptomology progression and age.
Figure 2
Figure 2
Differential diagnosis of eosinophilic esophagitis. CMV: Cytomegalovirus; GERD: Gastroesophageal reflux disease; GI: Gastrointestinal; HSV: Herpes simplex virus.

Similar articles

References

    1. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood SE, Bonis PA, Burks AW, Chehade M, Collins MH, Dellon ES, Dohil R, Falk GW, Gonsalves N, Gupta SK, Katzka DA, Lucendo AJ, Markowitz JE, Noel RJ, Odze RD, Putnam PE, Richter JE, Romero Y, Ruchelli E, Sampson HA, Schoepfer A, Shaheen NJ, Sicherer SH, Spechler S, Spergel JM, Straumann A, Wershil BK, Rothenberg ME, Aceves SS. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011;128:3–20.e6; quiz 21. - PubMed
    1. Straumann A, Schoepfer A. Update on basic and clinical aspects of eosinophilic oesophagitis. Gut. 2014;63:1355–1363. - PubMed
    1. Kelley ML Jr, Frazer JP. Symptomatic mid-esophageal webs. JAMA. 1966;197:143–146. - PubMed
    1. Landres RT, Kuster GG, Strum WB. Eosinophilic esophagitis in a patient with vigorous achalasia. Gastroenterology. 1978;74:1298–1301. - PubMed
    1. Shiflett DW, Gilliam JH, Wu WC, Austin WE, Ott DJ. Multiple esophageal webs. Gastroenterology. 1979;77:556–559. - PubMed