Rare case of divided phrenic nerve variation: a cadaveric case report
- PMID: 38597949
- DOI: 10.1007/s00276-024-03341-w
Rare case of divided phrenic nerve variation: a cadaveric case report
Abstract
The phrenic nerve innervates the respiratory diaphragm, the primary muscle active during ventilation. The canonical path of the phrenic nerve originates from the cervical spine at C3-C5 spinal nerves and travels inferiorly through the neck and thoracic cavity to reach the diaphragm. During a cadaver dissection, a variation of the phrenic nerve was discovered in a 93-year-old male specimen. A traditional origin of the phrenic nerve was noted; however, the nerve branched into medial and lateral components at the level of the superior trunk of the brachial plexus. The branches reconnected at the apex of the aortic arch and continued inferiorly to innervate the ipsilateral diaphragm. This case study describes a rare type of branching of the phrenic nerve and explores its potential impact on clinical procedures.
Keywords: Anatomical variation; Brachial plexus; Neck anatomy; Phrenic nerve branching; Unilateral diaphragm paralysis.
© 2024. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.
Similar articles
-
Variant communication of phrenic nerve in neck.Surg Radiol Anat. 2019 Feb;41(2):151-152. doi: 10.1007/s00276-018-2123-0. Epub 2018 Oct 25. Surg Radiol Anat. 2019. PMID: 30361840
-
Intercostal nerve transfer for restoration of the diaphragm muscle function after phrenic nerve transfer in total brachial plexus avulsion.Clin Neurol Neurosurg. 2020 Oct;197:106085. doi: 10.1016/j.clineuro.2020.106085. Epub 2020 Jul 13. Clin Neurol Neurosurg. 2020. PMID: 32683197
-
Marked lateral deviation of the phrenic nerve due to variant origin and course of the thyrocervical trunk: a cadaveric study.Surg Radiol Anat. 2016 May;38(4):485-8. doi: 10.1007/s00276-015-1557-x. Epub 2015 Oct 5. Surg Radiol Anat. 2016. PMID: 26438272 Free PMC article.
-
A variation of the phrenic nerve: case report and review.Singapore Med J. 2007 Dec;48(12):1156-7. Singapore Med J. 2007. PMID: 18043847 Review.
-
Surgical anatomy of the diaphragm and the phrenic nerve.Chest Surg Clin N Am. 1998 May;8(2):281-94. Chest Surg Clin N Am. 1998. PMID: 9619305 Review.
Cited by
-
The course of the phrenic nerve in the neck region and its relationship with adjacent anatomical structures in the thoracic inlet.Surg Radiol Anat. 2024 Dec;46(12):1917-1928. doi: 10.1007/s00276-024-03476-w. Epub 2024 Oct 17. Surg Radiol Anat. 2024. PMID: 39420164
References
-
- Greer JP, Allan DC, Martin-Caraballo M, Lemke RP (1999) An overview of phrenic nerve and diaphragm muscle development in the perinatal rat. J Appl Physiol 86(3):779–786. https://doi.org/10.1152/jappl.1999.86.3.779 - DOI - PubMed
-
- Graves MJ, Henry BM, Hsieh WC et al (2017) Origin and prevalence of the accessory phrenic nerve: a meta-analysis and clinical appraisal. Clin Anat 30(8):1077–1082. https://doi.org/10.1002/ca.22956 - DOI - PubMed
-
- Hang D, Ellinas H, Dolinski SY (2018) Iatrogenic nerve injury resulting in respiratory failure after mediastinoscopy. Int J Anesthet Anesthesiol 5:077. https://doi.org/10.23937/2377-4630/1410077 - DOI
-
- Iwanaga J, Singh V, Takeda S et al (2022) Standardized statement for the ethical use of human cadaveric tissues in anatomy research papers: Recommendations from Anatomical Journal Editors-in-Chief. Clin Anat 35(34):526–528. https://doi.org/10.1002/ca.23849 - DOI - PubMed
-
- Lee JH, Kim HT, Choi IJ et al (2021) An unusual anatomical variant of the left phrenic nerve encircling the transverse cervical artery. Folia Morphol 80(4):1027–1031. https://doi.org/10.5603/fm.a2020.0131 - DOI
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous