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Comment
. 2024 Apr 23;121(17):e2405089121.
doi: 10.1073/pnas.2405089121. Epub 2024 Apr 10.

A life for a (shorter) life: The reproduction-longevity trade-off

Affiliations
Comment

A life for a (shorter) life: The reproduction-longevity trade-off

Rafaela S C Takeshita. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Competing interests statement:The author declares no competing interest.

Figures

Fig. 1.
Fig. 1.
Schematic of energy allocation during pregnancy. The mother experiences an energetic tradeoff that favors reproduction and minimizes somatic maintenance. This allocation strategy ensures offspring survival, but it accelerates maternal biological aging, resulting in a shorter lifespan.

Comment on

  • Pregnancy is linked to faster epigenetic aging in young women.
    Ryan CP, Lee NR, Carba DB, MacIsaac JL, Lin DTS, Atashzay P, Belsky DW, Kobor MS, Kuzawa CW. Ryan CP, et al. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2317290121. doi: 10.1073/pnas.2317290121. Epub 2024 Apr 8. Proc Natl Acad Sci U S A. 2024. PMID: 38588424 Free PMC article.

References

    1. Kirkwood T. B., Rose M. R., Evolution of senescence: Late survival sacrificed for reproduction. Philos. Trans. R. Soc. Lond. B Biol. Sci. 332, 15–24 (1991). - PubMed
    1. Williams G. C., Natural selection, the costs of reproduction, and a refinement of Lack’s principle. Am. Nat. 100, 687–690 (1966).
    1. Ryan C. P., et al. , Pregnancy is linked to faster epigenetic aging in young women. Proc. Natl. Acad. Sci. U.S.A. 121, e2317290121 (2024). - PMC - PubMed
    1. Kominiarek M. A., Rajan P., Nutrition recommendations in pregnancy and lactation. Med. Clin. 100, 1199–1215 (2016). - PMC - PubMed
    1. Pianka E. R., On r-and K-selection. Am. Nat. 104, 592–597 (1970).

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