Stressed out neutrophils drive metastasis
- PMID: 38599176
- DOI: 10.1016/j.immuni.2024.03.013
Stressed out neutrophils drive metastasis
Abstract
Stress hormones can contribute to cancer progression, but how immune cells play a role in this process is unclear. In a recent study in Cancer Cell, He et al. showed that glucocorticoids potentiate metastasis by skewing neutrophils toward pro-tumorigenic functions.
Copyright © 2024 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.Cancer Cell. 2024 Mar 11;42(3):474-486.e12. doi: 10.1016/j.ccell.2024.01.013. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402610 Free PMC article.
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