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Clinical Trial
. 1979 Jun 30;1(13):626-8.
doi: 10.5694/j.1326-5377.1979.tb119425.x.

Labetalol and bendrofluazide: comparison of their antihypertensive effects

J S Horvath, R J Caterson, P Collett, G G Duggin, D H Kelly, D J Tiller
Clinical Trial

Labetalol and bendrofluazide: comparison of their antihypertensive effects

J S Horvath et al. Med J Aust. .

Abstract

A randomized double-blind crossover trial of labetalol, bendrofluazide and placebo was carried out in 18 patients with mild to moderate hypertension. The reduction in blood pressure observed with labetalol and bendrofluazide was similar. The plasma levels of labetalol showed a significant correlation with changes in blood pressure (r = 0.07; P less than 0.021); and plasma level determinations of this drug may be of value in the management of patients who receive antihypertensive agents.

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